Found 23 datasets matching "leukocyte".
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Many pulmonary diseases preferentially affect the large airways or the alveoli. Although the mechanisms are often particular to each disease process, site-specific differences in leukocyte...
Search relevance: 140.52 | Views last month: 0 -
The program at this year's American Thoracic Society international conference included over 300 scientific and clinical symposia. In this report I have reviewed the data presented on two important...
Search relevance: 133.88 | Views last month: 0 -
Ozone exposure induces neuroendocrine stress response, which causes lymphopenia. We hypothesized that ozone-induced increases in stress hormones will temporally follow changes in circulating...
Search relevance: 100.44 | Views last month: 0 -
Leukocyte ingress into the synovium is a key process in the pathogenesis of rheumatoid arthritis and other inflammatory conditions. In this review, the role of endothelial cells in leukocyte...
Search relevance: 93.29 | Views last month: 0 -
The data consists of a series of tables containing individual identifiers; countrywide high-resolution (1 km × 1 km) minimum, mean, and maximum daily air temperature data estimated using hybrid...
Search relevance: 83.60 | Views last month: 0 -
Secretory leukocyte proteinase inhibitor and elafin are two low-molecular-mass elastase inhibitors that are mainly synthesized locally at mucosal sites. It is thought that their physicochemical...
Search relevance: 75.06 | Views last month: 0 -
Background The parallel plate flow chamber has become a mainstay for examination of leukocytes under physiologic flow conditions. Several design modifications have occurred over the...
Search relevance: 74.49 | Views last month: 0 -
We have identified four different mutations causing leukocyte adhesion deficiency (LAD) in the ITGB2 gene of patients from a highly inbred population. Two were novel single-bp deletions (1497delG...
Search relevance: 66.34 | Views last month: 0 -
Background Analysis of cell-selective gene expression for families of proteins of therapeutic interest is crucial when deducing the influence of genes upon complex traits and disease...
Search relevance: 58.88 | Views last month: 0 -
Background GPIIb/IIIa inhibitors abciximab and eptifibatide have been shown to inhibit platelet aggregation in ischemic heart disease. Our aim was to test the efficacy of abiciximab (Reo...
Search relevance: 42.50 | Views last month: 0 -
Inherited susceptibility to rheumatoid arthritis (RA) is associated with the DRB1 genes encoding the human leukocyte antigen (HLA)-DR4 and HLA-DR1 molecules. Transgenic mice expressing these...
Search relevance: 40.42 | Views last month: 0 -
Background: Tissue damage after ischemia and reperfusion involves leukocyte endothelial interactions mediated by cell adhesion molecules. This study was designed to determine the time...
Search relevance: 35.81 | Views last month: 0 -
Reactive antigenic epitopes on presumed autoantigens of biologic interest have been examined by many researchers. The central third complementarity-determining region (CDR3) residues of a human...
Search relevance: 35.64 | Views last month: 0 -
There is mounting evidence indicating that the synovial fibroblast is a direct effector of tissue injury and matrix remodeling in inflammatory synovitis. Through the elaboration of effector...
Search relevance: 34.10 | Views last month: 0 -
Background Blood leukocytes constitute two interchangeable sub-populations, the marginated and circulating pools. These two sub-compartments are found in normal conditions and are...
Search relevance: 32.48 | Views last month: 0 -
Background The autoimmune thyroid diseases (AITDs), comprising Graves' disease (GD) and Hashimoto's thyroiditis (HT), appear to develop as a result of complex interactions between...
Search relevance: 32.18 | Views last month: 2 -
Background: Recent investigations have shown that leukocyte activation is involved in the pathogenesis of ventilator-associated lung injury. This study was designed to investigate...
Search relevance: 31.02 | Views last month: 0 -
Genes in the human leukocyte antigen (HLA) region remain the most powerful disease risk genes in rheumatoid arthritis (RA). Several allelic variants of HLA-DRB1 genes have been associated with RA,...
Search relevance: 26.66 | Views last month: 0 -
Background The autoimmune thyroid diseases (AITDs), such as Graves' disease (GD) and Hashimoto's thyroiditis (HT), appear to develop as a result of complex interactions between...
Search relevance: 25.62 | Views last month: 0 -
This online resource provides supplementary items used to analyze data in the work, "Single-cell RNA sequencing characterization of Holstein cattle blood and milk immune cells during a chronic...
Search relevance: 24.76 | Views last month: 12