Found 28 datasets matching "liver-cells".
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Background Numerous investigations demonstrate a novel role of thyroid hormone as a modulator of signal transduction. Protein kinase C (PKC) is critical to the mechanism by which thyroid...
Search relevance: 178.77 | Views last month: 0 -
Impacts of U.S. Streams on the Lipidome of Zebrafish Liver Cells. This dataset is associated with the following publication: Zhen, H., Q. Teng, J. Mosley, T. Collette, Y. Yue, P. Bradley, and D....
Search relevance: 147.86 | Views last month: 0 -
Carbon nanotubes (CNTs) have great potential in industrial, consumer, and mechanical applications, based partly on their unique structural, optical and electronic properties. CNTs are commonly...
Search relevance: 123.75 | Views last month: 0 -
Background Liver fibrosis is the common sequel of chronic liver diseases. Recent studies have identified hepatic stellate cells as the primary cell type mediating hepatic fibrogenesis....
Search relevance: 114.35 | Views last month: 1 -
Background Liver sinusoidal endothelial cells (LSECs) react to different anti-actin agents by increasing their number of fenestrae. A new structure related to fenestrae formation could...
Search relevance: 97.73 | Views last month: 0 -
Background The hepatic stellate cell is the primary cell type responsible for the excessive formation and deposition of connective tissue elements during the development of hepatic...
Search relevance: 96.30 | Views last month: 2 -
Background Thyroid hormones are well known modulators of signal transduction. The effect of hyper- and hypo-thyroidism on diacylglycerol/protein kinase C (DAG/PKC) signaling in...
Search relevance: 67.42 | Views last month: 0 -
Background The role of lymphocytes in the specific defence against L. infantum has been well established, but the part played by polynuclear neutrophil (PN) cells in controlling visceral...
Search relevance: 66.14 | Views last month: 0 -
Background Tyrosinemia type I, the most severe disease of the tyrosine catabolic pathway is caused by a deficiency in fumarylacetoacetate hydrolase (FAH). A patient showing few of the...
Search relevance: 62.49 | Views last month: 0 -
Background The liver-derived McNtcp.24 cells transport bile acids and show distinctive responses to the two classes of conjugated bile acids. Whereas taurine-conjugated bile acids are...
Search relevance: 61.20 | Views last month: 0 -
Data were collected from Xenopus laevis tadpoles exposed to clothianidin and thiamethoxam in two concentrations each, 100 ppm and 20 ppm. Gene expression was generated from brains and livers, and...
Search relevance: 57.72 | Views last month: 0 -
This review provides a detailed overview of the current state of knowledge about the ultrastructure and dynamics of liver sinusoidal endothelial fenestrae. Various aspects of liver sinusoidal...
Search relevance: 53.92 | Views last month: 1 -
This work is part of a study investigating the movement of microcystin from aquatic to terrestrial ecosystems via trophic transfer. Little brown bats (Myotis lucifugus), feeding opportunistically...
Search relevance: 51.15 | Views last month: 0 -
Isopeptides (ε-peptides) of lysine, with a given Mw and low polydispersity (10–400 units), were synthesized to study the relationship between their chemical structure and biological effect. The...
Search relevance: 48.65 | Views last month: 1 -
Background Prostaglandin E2 (PGE2) has multiple physiologic roles mediated by G protein coupled receptors designated E-prostanoid, or "EP" receptors. Evidence supports an important role...
Search relevance: 47.96 | Views last month: 1 -
Bioactivity data for p,p'-DDD and analogues from ToxCast assays conducted in liver cells were sourced from the EPA’s CompTox Chemistry Dashboard. The links also provide access to the ToxCast assay...
Search relevance: 47.94 | Views last month: 0 -
Understanding biotransformation pathways in aquatic species is an integral part of ecological risk assessment with respect to the potential bioactivation of chemicals to more toxic metabolites....
Search relevance: 47.26 | Views last month: 0 -
The US EPA’s ToxCast program is designed to assess chemical perturbations of molecular and cellular endpoints using a variety of high-throughput screening (HTS) assays. However, existing HTS...
Search relevance: 45.21 | Views last month: 0 -
Background The search for an optimal experimental model in pharmacology is recently focused on (mini)pigs as they seem not only to be an alternative source of cells and tissues for...
Search relevance: 44.43 | Views last month: 0 -
CMV infection of liver transplant recipients: comparison of antigenemia and molecular biology assays
Background CMV is a major clinical problem in transplant recipients. Thus, it is important to use sensitive and specific diagnostic techniques to rapidly and accurately detect CMV...
Search relevance: 43.32 | Views last month: 0
