Found 47 datasets matching "membrane-protein".
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Background A partial cDNA clone from dog thyroid presenting a very significant similarity with an uncharacterized mouse EST sequence was isolated fortuitously. We report here the...
Search relevance: 222.98 | Views last month: 0 -
Background Although MP20 is the second most highly expressed membrane protein in the lens its function remains an enigma. Putative functions for MP20 have recently been inferred from its...
Search relevance: 195.89 | Views last month: 0 -
A genome-wide analysis was carried out on patterns of the classified polytopic membrane protein families, and the distribution of conserved amino acids and motifs in the transmembrane helix...
Search relevance: 166.62 | Views last month: 0 -
The present invention provides porous media or membranes having a surface coating that includes a first coating of a cross-linked terpolymer and a second coating comprising a copolymer or a...
Search relevance: 81.27 | Views last month: 0 -
A process for obtaining protein preparations with constant functional properties, comprises extraction from a protein containing raw material, eg leguminous plants, cereals or oil seeds. The raw...
Search relevance: 66.44 | Views last month: 0 -
Background Pelvic floor disorders affect almost 50% of aging women. An important role in the pelvic floor support belongs to the levator ani muscle. The p27/kip1 (p27) protein,...
Search relevance: 60.78 | Views last month: 1 -
A landmark investigation into the genetic basis of murine progressive ankylosis has clarified the physiologic role of extracellular inorganic pyrophosphate (ePPi) in suppressing pathologic...
Search relevance: 59.10 | Views last month: 0 -
Background One mechanism that directs the action of the second messengers, cAMP and diacylglycerol, is the compartmentalization of protein kinase A (PKA) and protein kinase C (PKC)....
Search relevance: 58.42 | Views last month: 0 -
Background Members of the p24 (p24/gp25L/emp24/Erp) family of proteins have been shown to be critical components of the coated vesicles that are involved in the transportation of cargo...
Search relevance: 58.20 | Views last month: 0 -
Background To maintain organelle integrity, resident proteins must segregate from itinerant cargo during secretory transport. However, Golgi resident enzymes must have intimate access to...
Search relevance: 57.93 | Views last month: 0 -
Background NF1 refers to type 1 neurofibromatosis syndrome, which has been linked with mutations of the large NF1 gene. NF1 tumor suppressor protein, neurofibromin, has been shown to...
Search relevance: 57.17 | Views last month: 0 -
Background Virulence genes on Salmonella pathogenicity island 1 (SPI1) are coordinately regulated by HilA, a member of the OmpR/ToxR family of transcription factors. Although a great...
Search relevance: 56.83 | Views last month: 0 -
This review focuses on the mechanisms of stress response in the synovial tissue of rheumatoid arthritis. The major stress factors, such as heat stress, shear stress, proinflammatory cytokines and...
Search relevance: 55.68 | Views last month: 1 -
Background Cystinosis is an autosomal recessive disorder characterised by an intralysosomal accumulation of cystine, and affected individuals progress to end-stage renal failure before...
Search relevance: 54.35 | Views last month: 0 -
Background The delta(δ)-opioid receptors belong to the G protein-coupled receptors and in vitro studies have shown that δ-opioid receptors undergo an internalization process in response...
Search relevance: 54.27 | Views last month: 0 -
Background Bone morphogenetic proteins (BMPs) and transforming growth factor-βs (TGF-βs) are important regulators of bone repair and regeneration. BMP-2 and TGF-β1 have been shown to...
Search relevance: 54.16 | Views last month: 0 -
Background Exported proteases are commonly associated with virulence in bacterial pathogens, yet there is a paucity of information regarding their role in Mycobacterium tuberculosis....
Search relevance: 53.92 | Views last month: 0 -
Tamoxifen, a potent anticancer agent known to interrupt the enhanced estrogen activity of malignant mammary gland cells, was recently approved by the Food and Drug Administration (FDA) for the...
Search relevance: 53.88 | Views last month: 0 -
Background Dehydrins are known as Group II late embryogenesis abundant proteins. Their high hydrophilicity and thermostability suggest that they may be structure stabilizers with...
Search relevance: 53.40 | Views last month: 0 -
Background The L-type Ca2+ channel formed by the dihydropyridine receptor (DHPR) of skeletal muscle senses the membrane voltage and opens the ryanodine receptor (RyR1). This...
Search relevance: 52.75 | Views last month: 0
