Found 5 datasets matching "mhc-peptide-binding".
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Background Major histocompatibility complex (MHC) molecules present peptides to T lymphocytes. It is of critical biological and medical importance to elucidate how different MHC alleles...
Search relevance: 395.96 | Views last month: 1 -
Background Increasing evidence suggests that the effect of HLA-E on Natural Killer (NK) cell activity can be affected by the nature of the peptides bound to this non-classical, MHC class...
Search relevance: 354.57 | Views last month: 1 -
Background Quantitative information on the types of inter-atomic interactions at the MHC-peptide interface will provide insights to backbone/sidechain atom preference during binding....
Search relevance: 231.17 | Views last month: 0 -
There is provided a tolerogenic human peptide, capable of binding to an MHC class I or II molecule without further antigen processing, for use in the treatment and/or prevention of multiple...
Search relevance: 118.41 | Views last month: 0 -
T-cell epitopes represent sampled environmental- and self-peptides loaded into major histocompatibility complex (MHC) proteins. Bioinformatic tools have been produced to predict these interactions...
Search relevance: 83.99 | Views last month: 0