• Organization: U.S. Environmental Protection Agency
• Updated: 2016-07-01

Background: Trends in male reproductive health have been reported for increased rates of testicular germ cell tumors, low semen quality, cryptorchidism, and hypospadias, which have been associated...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

We report the findings of an animal experiment onboard STS-135 investigating the molecular aspects of the impact of spaceflight on retinal biology by performing differential gene expression...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

We report the findings of an animal experiment onboard STS-135 investigating the molecular aspects of the impact of spaceflight on retinal biology by performing differential gene expression...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

We report the findings of an animal experiment onboard STS-135 investigating the molecular aspects of the impact of spaceflight on retinal biology by performing differential gene expression...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

The aim of this study was to explore the molecular profile of proliferating rheumatoid arthritis synovial fibroblasts (RA-SF). Total RNA was extracted from two cultures of RA-SF (low-density [LD]...

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• Organization: U.S. Environmental Protection Agency
• Updated: 2025-04-07

Dataset for S. Sakamuru, et al., 'Profiling the Tox21 Compound Library for Their Inhibitory Effects on Cytochrome P450 Enzymes' published in Int'l Journal of Molecular Sciences, DOI...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

The objective of the Rodent Research-10 Mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue regeneration in space. To this end,...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

We examined molecular responses using transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy, 1 GeV proton (1H) and 15 cGy, 1 GeV/nucleon (n) iron (56Fe) particles 1,...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

We examined molecular responses using transcriptome profiling in isolated left ventricular murine cardiomyocytes to 90 cGy, 1 GeV proton (1H) and 15 cGy, 1 GeV/nucleon (n) proton (56Fe) particles...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

['Spaceflight uniquely alters the physiology of both human cells and microbial pathogens, stimulating cellular and molecular changes directly relevant to infectious disease. However, the influence...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

This study was conducted to uncover the underlying molecular mechanisms by which microgravity impacts cell wall architecture in the model plant Arabidopsis thaliana using the Vegetable Production...

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• Organization: Department of Agriculture
• Updated: 2025-05-06

Deep sequencing technologies were used to construct the first adult female Culicoides sonorensis reference transcriptome. Genetic and genomic tools for Culicoides biting midges are lacking,...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

Microgravity leads to a 10-15% loss of bone mass in astronauts during space flight. Osteoclast is the multinucleated bone resorbing cell. In this study we used NASA developed ground based Rotary...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

Microgravity leads to a 10-15% loss of bone mass in astronauts during space flight. Osteoclast is the multinucleated bone resorbing cell. In this study we used NASA developed ground based Rotary...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

The objective of the Rodent Research-10 mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue regeneration in space. To this end,...

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• none
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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

The objective of the Rodent Research-10 mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue regeneration in space. To this end,...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

Transforming growth factor beta-1 (TGFbeta) is a tumor suppressor during the initial stage of tumorigenesis, but it can switch to a tumor promoter during neoplastic progression. Ionizing radiation...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

Age plays a major role in tumor incidence and is an important consideration when modeling the carcinogenesis process or estimating cancer risks. Epidemiological data show that from adolescence...

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• Organization: Department of Agriculture
• Updated: 2024-02-13

The ascomycete Neofusicoccum parvum, one of the causal agents of Botryosphaeria dieback, is a destructive wood‐infecting fungus and a serious threat to grape production worldwide. The capability...

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