Found 25 datasets matching "mouse-genome".
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MGI is the international database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data to facilitate the study of human health and disease.
Search relevance: 111.42 | Views last month: 5 -
Background Using genetic distances measured from exons, it has been observed that the mutation rate is not constant along mammalian chromosomes. Exons constitute only 1% of the human...
Search relevance: 72.90 | Views last month: 0 -
Gene expression changes induced by acute skeletal muscle unloading which leads to physiological changes including muscle atrophy fibre-type switching and loss of ability to transition between...
Search relevance: 54.34 | Views last month: 0 -
Background The presynaptic protein α-synuclein is involved in a range of neurodegenerative diseases. Here we analyze potential compensatory mechanisms in α-synuclein null mutant mice....
Search relevance: 51.72 | Views last month: 1 -
Cesium-137 is a radionuclide of concern in fallout from reactor accidents or nuclear detonations. When ingested or inhaled it can expose the entire body for an extended period of time potentially...
Search relevance: 50.00 | Views last month: 0 -
Cesium-137 is a radionuclide of concern in fallout from reactor accidents or nuclear detonations. When ingested or inhaled it can expose the entire body for an extended period of time potentially...
Search relevance: 50.00 | Views last month: 0 -
Background Capping protein (CP), a heterodimer of α and β subunits, is found in all eukaryotes. CP binds to the barbed ends of actin filaments in vitro and controls actin assembly and...
Search relevance: 49.87 | Views last month: 0 -
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the production of autoantibodies to a wide range of self-antigens. Recent genome screens have implicated...
Search relevance: 41.87 | Views last month: 0 -
Background Previous studies by Volloch and coworkers have reported that during the expression of high levels of β-globin mRNA in the spleen of anemic mice, they could also detect small...
Search relevance: 41.09 | Views last month: 0 -
The aim of our research is to clarify the mechanisms generating heterogeneity in response to C-ion irradiation that arise from individual genetic variations in humans. In this study we performed...
Search relevance: 41.09 | Views last month: 0 -
The aim of our research is to clarify the mechanisms generating heterogeneity in response to C-ion irradiation that arise from individual genetic variations in humans. In this study we performed...
Search relevance: 41.09 | Views last month: 0 -
['Cancer-causing genome instability is a major concern during space travel due to exposure of astronauts to potent sources of high-linear energy transfer (LET) ionizing radiation. Hematopoietic...
Search relevance: 40.70 | Views last month: 0 -
Accumulating data support the concept that ionizing radiation therapy (RT) has the potential to convert the tumor into an in situ individualized vaccine; however this potential is rarely realized...
Search relevance: 39.79 | Views last month: 0 -
Accumulating data support the concept that ionizing radiation therapy (RT) has the potential to convert the tumor into an in situ individualized vaccine; however this potential is rarely realized...
Search relevance: 39.39 | Views last month: 0 -
Background A partial cDNA clone from dog thyroid presenting a very significant similarity with an uncharacterized mouse EST sequence was isolated fortuitously. We report here the...
Search relevance: 37.12 | Views last month: 0 -
Bats of the genus Lasiurus occur throughout the Americas and have diversified into at least 20 species among three subgenera. The hoary bat (Lasiurus cinereus, or synonymously, Aeorestes cinereus)...
Search relevance: 35.49 | Views last month: 0 -
Microgravity leads to a 10-15% loss of bone mass in astronauts during space flight. Osteoclast is the multinucleated bone resorbing cell. In this study we used NASA developed ground based Rotary...
Search relevance: 35.33 | Views last month: 0 -
This is a genome-wide approach to identifying genes persistently induced in the mouse mammary gland by acute whole body low dose ionizing radiation (10cGy) 1 and 4 weeks after exposure. Gene...
Search relevance: 34.97 | Views last month: 0 -
Microgravity leads to a 10-15% loss of bone mass in astronauts during space flight. Osteoclast is the multinucleated bone resorbing cell. In this study we used NASA developed ground based Rotary...
Search relevance: 34.97 | Views last month: 0 -
This is a genome-wide approach to identifying genes persistently induced in the mouse mammary gland by acute whole body low dose ionizing radiation (10cGy) 1 and 4 weeks after exposure. Gene...
Search relevance: 34.97 | Views last month: 0