Found 46 datasets matching "mrna-levels".
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Background Soluble guanylyl cyclase (sGC) is the main receptor for nitric oxide (NO) when the latter is produced at low concentrations. This enzyme exists mainly as a heterodimer...
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Relative mRNA levels from maize organs have been quantified by hybridization to maize arrays fabricated with 5,376 unique expressed sequence tag clones. mRNAs from embryos, three vegetative organs...
Search relevance: 106.15 | Views last month: 0 -
Background Fracture healing slows with age. While 6-week-old rats regain normal bone biomechanics at 4 weeks after fracture, one-year-old rats require more than 26 weeks. The possible...
Search relevance: 60.12 | Views last month: 0 -
Background Vascular endothelial growth factor (VEGF) mRNA levels increase in rat skeletal muscle after a single bout of acute exercise. We assessed regional differences in VEGF165 mRNA...
Search relevance: 58.05 | Views last month: 0 -
The efficiency of programmed ribosomal frameshifting in decoding antizyme mRNA is the sensor for an autoregulatory circuit that controls cellular polyamine levels in organisms ranging from the...
Search relevance: 57.92 | Views last month: 0 -
Constitutive mRNA expression and secretion of proinflammatory and anti-inflammatory cytokines was comparatively analyzed in rheumatoid arthritis (RA) synovial fibroblasts (SFB), isolated from...
Search relevance: 57.54 | Views last month: 0 -
Background The cyclin-dependent kinase inhibitor p27Kip1 is essential for proper control of cell cycle progression. The levels of p27Kip1 are regulated by several mechanisms including...
Search relevance: 56.44 | Views last month: 0 -
Background Flavopiridol, a flavonoid currently in cancer clinical trials, inhibits cyclin-dependent kinases (CDKs) by competitively blocking their ATP-binding pocket. However, the...
Search relevance: 55.07 | Views last month: 0 -
Background Previous studies by Volloch and coworkers have reported that during the expression of high levels of β-globin mRNA in the spleen of anemic mice, they could also detect small...
Search relevance: 53.91 | Views last month: 0 -
Background Expression of the retinoic acid receptor β2 (RAR-β2), a putative tumor suppressor gene, is reduced in various human cancers, including squamous cell carcinomas (SCC) of the...
Search relevance: 53.26 | Views last month: 1 -
This data set includes capture location, date, sex, and results of molecular gene transcription analysis for sea otters (Enhydra lutris) sampled in western Prince William Sound (WPWS), Alaska and...
Search relevance: 52.68 | Views last month: 0 -
Background In addition to immune cells, many other cell types are known to produce cytokines. Cultured normal mouse gallbladder epithelial cells, used as a model system for gallbladder...
Search relevance: 50.38 | Views last month: 0 -
Background Nocturnin was originally identified by differential display as a circadian clock regulated gene with high expression at night in photoreceptors of the African clawed frog,...
Search relevance: 50.06 | Views last month: 0 -
Interleukin-1 receptor antagonist (IL-1Ra) is a natural IL-1 inhibitor possessing anti-inflammatory properties. IL-1Ra is produced as different isoforms, one secreted (sIL-1Ra) and three...
Search relevance: 48.38 | Views last month: 0 -
Background The availability of complete genome sequences enables all the members of a gene family to be identified without limitations imposed by temporal, spatial or quantitative...
Search relevance: 48.24 | Views last month: 0 -
Background HIV-1 is known to play a critical role in the pathogenesis of AIDS-associated Kaposi's sarcoma (KS). However, it remains controversial whether KS cells are target cells for...
Search relevance: 48.08 | Views last month: 1 -
Background Several lines of evidence strongly suggest that agouti-related peptide (AGRP) plays a key role in the regulation of metabolic function but ablation of the AGRP gene has no...
Search relevance: 47.91 | Views last month: 0 -
Background We previously identified and characterized a novel 55 kDa nuclear protein, termed nmt55/p54nrb, whose expression was decreased in a subset of human breast tumors. The...
Search relevance: 46.32 | Views last month: 0 -
Dedication This article is dedicated to the memory of Sue Kim Hanson, a graduate student in the department of Pathology and Laboratory Medicine at Boston University School of Medicine,...
Search relevance: 45.74 | Views last month: 1 -
The main manifestation of systemic sclerosis (SSc) is the overproduction of extracellular matrix, predominantly type I collagen. This study was undertaken to evaluate the effects of noncytotoxic...
Search relevance: 43.89 | Views last month: 1
