• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background To learn about the molecular etiology of strabismus, we are studying the genetic basis of 'congenital fibrosis of the extraocular muscles' (CFEOM). These syndromes are...

• html

• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

We sought to comprehensively elucidate the transcriptomic underpinnings of microgravity-induced muscle phenotypes in mice by evaluating both differential gene expression (DGE) and changes in...

• none
• none
• none
• none

• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

It is well established that microgravity exposure causes significant muscle weakness and atrophy via muscle unloading. On Earth, muscle unloading leads to a disproportionate loss in muscle force...

• none
• none
• none
• none
• none

• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

Upon weightlessness and microgravity deleterious effects on the neurosensory and neurovestibular systems haematological changes and deconditioning of musculoskeletal cardiovascular and...

• html

• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

Upon weightlessness and microgravity deleterious effects on the neurosensory and neurovestibular systems haematological changes and deconditioning of musculoskeletal cardiovascular and...

• html

• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background Vascular endothelial growth factor (VEGF) mRNA levels increase in rat skeletal muscle after a single bout of acute exercise. We assessed regional differences in VEGF165 mRNA...

• html

• Organization: U.S. Department of Health & Human Services
• Updated: 2025-03-17

Cisatracurium Besylate is a prescription injectable medication used intravenously to relax muscles during surgery or mechanical ventilation. Manufactured by Gland Pharma Limited, it comes in...

• html

• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background Laryngeal dysfunction can be a salient feature in the clinical symptomatology of speakers diagnosed with Amyotrophic Lateral Sclerosis (ALS). In addition to dysphonia,...

• html

• Organization: U.S. Department of Health & Human Services
• Updated: 2025-03-17

Theophylline is a prescription medication available as extended-release tablets (400mg and 600mg) for oral use, manufactured by Glenmark Pharmaceuticals Inc., USA. It belongs to the methylxanthine...

• html

• Organization: U.S. Department of Health & Human Services
• Updated: 2025-03-17

Tropicamide is an ophthalmic solution used to dilate the pupils during eye exams. This prescription drug, manufactured by Sandoz Inc, works as an anticholinergic to temporarily widen the pupil and...

• html

• Organization: U.S. Department of Health & Human Services
• Updated: 2025-03-17

Vecuronium Bromide is a prescription injectable medication used intravenously as a neuromuscular blocker to relax muscles during surgery or intubation. Available in 10 mg and 20 mg vials as a...

• html

• Organization: U.S. Department of Health & Human Services
• Updated: 2025-03-17

Silodosin is a prescription drug that helps relieve symptoms of an enlarged prostate, like difficulty urinating. It works by relaxing muscles in the prostate and bladder as an alpha-adrenergic...

• html

• Organization: U.S. Department of Health & Human Services
• Updated: 2025-03-17

Tizanidine Hydrochloride is a generic prescription medication that helps relieve muscle spasms caused by conditions like multiple sclerosis or spinal cord injuries. It works as a central alpha-2...

• html

• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background Morphological and electrophysiological studies of ischemic muscles in peripheral arterial disease disclosed evidence of denervation and fibre atrophy. The purpose of the...

• html

• Organization: U.S. Department of Health & Human Services
• Updated: 2025-03-17

Cardura (doxazosin mesylate) is a prescription medication used to treat high blood pressure and symptoms of an enlarged prostate. It comes as oral tablets in strengths of 1 mg, 2 mg, 4 mg, and 8...

• html

• Organization: U.S. Department of Health & Human Services
• Updated: 2025-03-17

DAXXIFY is a prescription injectable form of botulinum toxin type A, manufactured by Revance Therapeutics, Inc., used to temporarily improve the appearance of moderate to severe frown lines...

• html

• Organization: U.S. Department of Health & Human Services
• Updated: 2025-03-17

Dutasteride and Tamsulosin Hydrochloride is a prescription capsule combining two medications to treat symptoms of an enlarged prostate (benign prostatic hyperplasia). Dutasteride reduces prostate...

• html

• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background Congenital fibrosis of the extraocular muscles type 1 (CFEOM1) is an autosomal dominant eye movement disorder linked to the pericentromere of chromosome 12 (12p11.2 - q12)....

• html

• Organization: National Aeronautics and Space Administration
• Updated: 2025-07-14

Microgravity has a dramatic impact on human physiology illustrated in particular with skeletal muscle impairment. A thorough understanding of the mechanisms leading to loss of muscle mass and...

• html

• Organization: National Aeronautics and Space Administration
• Updated: 2025-07-14

Microgravity has a dramatic impact on human physiology illustrated in particular with skeletal muscle impairment. A thorough understanding of the mechanisms leading to loss of muscle mass and...

• html