Found 54 datasets matching "mutants".
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Background Starting from Benzer's initiative, the approach of forward genetics has been widely used to isolate mutations affecting learning and memory. For this aim, mainly the...
Search relevance: 129.08 | Views last month: 0 -
Understanding plant adaptive responses to the space environment is a requisite for enabling space farming. Spaceflight produce deleterious effects on plant cells particularly affecting ribosome...
Search relevance: 83.18 | Views last month: 0 -
Epigenetic changes in the DNA methylome are increasingly shown to play an integral role in regulating gene expression necessary for plants adaption to environmental stressors. Plants subjected to...
Search relevance: 81.36 | Views last month: 0 -
Background Factors that affect flowering vary among different plant species, and in the grasses in particular the exact mechanism behind this transition is not fully understood. The...
Search relevance: 80.85 | Views last month: 0 -
Epigenetic changes in the DNA methylome are increasingly shown to play an integral role in regulating gene expression necessary for plants’ adaption to environmental stressors. Plants subjected to...
Search relevance: 79.07 | Views last month: 0 -
Traveling to nearby extraterrestrial objects having a reduced gravity level (partial gravity) compared to Earth s gravity is becoming a realistic objective for space agencies. The use of plants as...
Search relevance: 73.03 | Views last month: 0 -
Background FtsZ, the major cytoskeletal protein in bacterial cytokinesis, assembles in vitro into protofilaments, which can further associate into sheets, bundles or tubes. We have...
Search relevance: 51.21 | Views last month: 1 -
Background Nuclear pore complexes (NPCs) are essential for facilitated, directional nuclear transport; however, the mechanism by which ~30 different nucleoporins (nups) are assembled...
Search relevance: 50.59 | Views last month: 0 -
Background A non-pathogenic species of coryneform bacteria, Corynebacterium glutamicum, was originally isolated as an L-glutamate producing bacterium and is now used for fermentative...
Search relevance: 48.03 | Views last month: 0 -
The Mitotic Exit Network (MEN) proteins – including the protein kinase Cdc15 and the protein phosphatase Cdc14 – are essential for exit from mitosis inSaccharomyces cerevisiae.To identify...
Search relevance: 46.86 | Views last month: 0 -
Background Endoplasmic reticulum retention of misfolded cystic fibrosis transmembrane conductance regulator (CFTR) mutants and their rapid degradation is the major cause of cystic...
Search relevance: 41.21 | Views last month: 0 -
Background Somatic cell mutants can be informative in the analysis of a wide variety of cellular processes. The use of map-based positional cloning strategies in somatic cell hybrids to...
Search relevance: 40.45 | Views last month: 1 -
Whole seedlings of wild type (4d) and atm mutants (4d) have been analyzed after a gamma ray irradiation of 0.75h 1.5h 3h & 5h (time course). Roots of wt (4d) atm (3d) and atr (4d) mutants have...
Search relevance: 40.00 | Views last month: 0 -
The present invention provides methods for building DNA constructs in vitro, transforming such constructs into competent Bacillus strains with good efficiency, and generating populations of...
Search relevance: 39.73 | Views last month: 0 -
Background Genetic screens in Drosophila have provided a wealth of information about a variety of cellular and developmental processes. It is now possible to screen for mutant phenotypes...
Search relevance: 39.42 | Views last month: 0 -
Background In most organisms proper reductional chromosome segregation during meiosis I is strongly correlated with the presence of crossover recombination structures (chiasmata);...
Search relevance: 39.11 | Views last month: 0 -
Background The function of the thymic microenvironment is to promote thymocyte maturation, in part via regulation of thymocyte proliferation and cell death. Defects in fetal thymic...
Search relevance: 38.44 | Views last month: 0 -
Background Annotations of completely sequenced genomes reveal that nearly half of the genes identified are of unknown function, and that some belong to uncharacterized gene families. To...
Search relevance: 35.41 | Views last month: 0 -
Several Francisella spp. including F. noatunensis are regarded as important emerging pathogens of wild and farmed fish. However, very few studies have investigated the virulence factors that allow...
Search relevance: 34.98 | Views last month: 0 -
Background The COP9/signalosome (CSN), a multiprotein complex consisting of eight subunits, is implicated in a wide variety of regulatory processes including cell cycle control, signal...
Search relevance: 34.63 | Views last month: 0
