Found 13 datasets matching "mycobacterium-tuberculosis".
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Background The prevalence of infections by Mycobacterium tuberculosis and non-tuberculous Mycobacterium species in the HIV-infected patient population in Colombia was uncertain despite...
Search relevance: 153.67 | Views last month: 1 -
Background The ability of Mycobacterium tuberculosis to survive and replicate in macrophages is crucial for the mycobacterium's ability to infect the host and cause tuberculosis. To...
Search relevance: 149.93 | Views last month: 0 -
Background The gene encoding the inorganic pyrophosphatase (PPase) of the intracellular pathogen Legionella pneumophila is induced during intracellular infection, but is constitutively...
Search relevance: 147.96 | Views last month: 0 -
Background Exported proteases are commonly associated with virulence in bacterial pathogens, yet there is a paucity of information regarding their role in Mycobacterium tuberculosis....
Search relevance: 145.97 | Views last month: 0 -
Background The genome of Mycobacterium tuberculosis H37Rv has five copies of a cluster of genes known as the ESAT-6 loci. These clusters contain members of the CFP-10 (lhp) and ESAT-6...
Search relevance: 134.02 | Views last month: 0 -
Background Pyrazinamide (PZA) is among the first-line drugs for the treatment of tuberculosis. In vitro, it kills semidormant mycobacteria only at low pH. The purpose of this study was...
Search relevance: 131.46 | Views last month: 0 -
Background Since the sterilising activity of new antituberculosis drugs is difficult to assess by conventional phase III studies, surrogate methods related to eventual relapse rates are...
Search relevance: 121.80 | Views last month: 0 -
This was a head-to-head comparison of three FDA-approved tests for TB infection (Tuberculin Skin Test, QuantiFERON-TB Gold In-Tube, and T-SPOT.TB) in populations at high risk of latent TB...
Search relevance: 105.68 | Views last month: 0 -
Background A prospective observational study was done to describe nonbacterial pulmonary complications in hospitalized patients with human immunodeficiency virus (HIV) infection. ...
Search relevance: 88.87 | Views last month: 0 -
Background: Whole-genome comparisons can provide great insight into many aspects of biology. Until recently, however, comparisons were mainly possible only between distantly related...
Search relevance: 61.09 | Views last month: 0 -
Background: The arginine repressor ArgR/AhrC is a transcription factor universally conserved in bacterial genomes. Its recognition signal (the ARG box), a weak palindrome, is also...
Search relevance: 60.53 | Views last month: 0 -
Background: Genome comparisons have revealed major lateral gene transfer between the three primary kingdoms of life - Bacteria, Archaea, and Eukarya. Another important evolutionary...
Search relevance: 47.92 | Views last month: 1 -
The aim of this study was to analyze the differential effects of three anti-CD4 monoclonal antibodies (mAbs) (with distinct epitope specifities) in the treatment of rat adjuvant arthritis (AA) and...
Search relevance: 44.07 | Views last month: 0
