Found 17 datasets matching "neutrophil".
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Background Extended culture of monocytes and fibroblasts in three-dimensional collagen gels leads to degradation of the gels (see linked study in this issue, "Fibroblasts and monocytes...
Search relevance: 126.73 | Views last month: 0 -
Background Evidence suggests that both the migration and activation of neutrophils into the airway is of importance in pathological conditions such as pulmonary emphysema. In the present...
Search relevance: 85.05 | Views last month: 0 -
Background The role of lymphocytes in the specific defence against L. infantum has been well established, but the part played by polynuclear neutrophil (PN) cells in controlling visceral...
Search relevance: 77.09 | Views last month: 0 -
Background Lipopolysaccharide (endotoxin) from the cell wall of Gram-negative bacteria is a potent trigger for the release of host-derived inflammatory mediators. The relationship...
Search relevance: 55.04 | Views last month: 1 -
The neutrophil azurophil granule constituent proteinase 3 (PR3) is the principal antigen for anti-neutrophil cytoplasmic antibodies (ANCA) in Wegener's granulomatosis. The conformation of the...
Search relevance: 53.30 | Views last month: 0 -
Anti-neutrophil cytoplasmic antibodies (ANCA) have become important diagnostic markers of small vessel vasculitides characterized by focal necrotizing lesions of vessel walls and accumulation of...
Search relevance: 48.88 | Views last month: 0 -
Secretory leukocyte proteinase inhibitor and elafin are two low-molecular-mass elastase inhibitors that are mainly synthesized locally at mucosal sites. It is thought that their physicochemical...
Search relevance: 47.35 | Views last month: 0 -
Recent advances suggest that toll-like receptors, various cytokines, cicosanoids, free radicals and macrophage migration inhibitory factor (MIF) play an important role in the pathobiology of...
Search relevance: 44.08 | Views last month: 3 -
The pathogenesis of systemic vasculitis is complex and is likely to involve many mechanisms. There is a growing body of evidence that T cells may contribute to the pathogenesis of anti-neutrophil...
Search relevance: 35.69 | Views last month: 1 -
Reactive antigenic epitopes on presumed autoantigens of biologic interest have been examined by many researchers. The central third complementarity-determining region (CDR3) residues of a human...
Search relevance: 34.09 | Views last month: 0 -
Background: Elevated plasma lactate has been shown to correlate with mortality in patients with septic shock. Heat stress prior to sepsis has resulted in reduction in acute lung injury...
Search relevance: 32.92 | Views last month: 0 -
Background: Recent investigations have shown that leukocyte activation is involved in the pathogenesis of ventilator-associated lung injury. This study was designed to investigate...
Search relevance: 32.48 | Views last month: 0 -
Background Inflammatory cells are believed to play a prominent role during tissue repair and remodeling. Since repair processes develop and mature over extended time frames, the present...
Search relevance: 31.86 | Views last month: 0 -
This online resource provides supplementary items used to analyze data in the work, "Single-cell RNA sequencing characterization of Holstein cattle blood and milk immune cells during a chronic...
Search relevance: 25.95 | Views last month: 12 -
Background The timed-sequential chemotherapy regimen consisting of etoposide, mitoxantrone and cytarabine (EMA) is an effective therapy for relapsed or refractory acute myelogenous...
Search relevance: 25.15 | Views last month: 0 -
Background Food allergies are generally associated with gastrointestinal upset, but in many patients systemic reactions occur. However, the systemic effects of food allergies are poorly...
Search relevance: 25.12 | Views last month: 2 -
The VA National Clozapine Registry tracks the health and demographics of patients who have been prescribed clozapine by the VA. Clozapine, or the brand name Clozaril, is a drug used to treat the...
Search relevance: 21.51 | Views last month: 8
