Found 9 datasets matching "orthologous-proteins".
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Background: Standard archival sequence databases have not been designed as tools for genome annotation and are far from being optimal for this purpose. We used the database of Clusters...
Search relevance: 152.98 | Views last month: 0 -
Background Detection of changes in a protein's evolutionary rate may reveal cases of change in that protein's function. We developed and implemented a simple relative rates test in an...
Search relevance: 144.42 | Views last month: 0 -
Background The metalloprotease-disintegrin family, or ADAM, proteins, are implicated in cell-cell interactions, cell fusion, and cell signaling, and are widely distributed among metazoan...
Search relevance: 69.49 | Views last month: 0 -
Background The availability of multiple complete genome sequences from diverse taxa prompts the development of new phylogenetic approaches, which attempt to incorporate information...
Search relevance: 59.33 | Views last month: 2 -
Background Gene fusions can be used as tools for functional prediction and also as evolutionary markers. Fused genes often show a scattered phyletic distribution, which suggests a role...
Search relevance: 54.59 | Views last month: 3 -
Background Nuclear DNA sequences provide genetic information that complements studies using mitochondrial DNA. Some 'universal' primer sets have been developed that target introns within...
Search relevance: 48.78 | Views last month: 0 -
Background The search for an optimal experimental model in pharmacology is recently focused on (mini)pigs as they seem not only to be an alternative source of cells and tissues for...
Search relevance: 45.47 | Views last month: 0 -
Background Gene duplications have a major role in the evolution of new biological functions. Theoretical studies often assume that a duplication per se is selectively neutral and that,...
Search relevance: 43.31 | Views last month: 0 -
Background Horizontal gene transfer (HGT) played an important role in shaping microbial genomes. In addition to genes under sporadic selection, HGT also affects housekeeping genes and...
Search relevance: 39.26 | Views last month: 0
