• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background Bisphosphonates are indicated in the prevention and treatment of osteoporosis. However, bone mineral density (BMD) continues to decline in up to 15% of bisphosphonate users....

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Inhibitors of the 3-hydroxy-3-methylglutaryl coenzyme A reductase enzyme have recently been shown to stimulate bone formation in rodents both in vitro and in vivo. In bone cells, these inhibitors...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

Prolonged skeletal unloading through bedrest results in bone loss similar to that observed in elderly osteoporotic patients but with an accelerated timeframe. This rapid effect on weight-bearing...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

Prolonged skeletal unloading through bedrest results in bone loss similar to that observed in elderly osteoporotic patients but with an accelerated timeframe. This rapid effect on weight-bearing...

• html

• Organization: National Aeronautics and Space Administration
• Updated: 2025-04-23

Prolonged skeletal unloading through bedrest results in bone loss similar to that observed in elderly osteoporotic patients but with an accelerated timeframe. This rapid effect on weight-bearing...

• html