Found 24 datasets matching "prostate-cancer".
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DNA microarrays were used to examine the temporal program of gene expression following treatment of a human prostate cancer cell line with androgen. Significant changes in levels of transcripts of...
Search relevance: 236.96 | Views last month: 0 -
Background The cyclin-dependent kinase inhibitor p27 is a putative tumor suppressor that is downregulated in the majority of human prostate cancers. The mechanism of p27 down-regulation...
Search relevance: 233.75 | Views last month: 0 -
Datasets used in ORD-023417: Identification of Androgen Receptor Modulators in a Prostate Cancer Cell Line Microarray Compendium. This dataset is associated with the following...
Search relevance: 229.25 | Views last month: 0 -
The present invention provides a method of treating prostate cancer comprising administering to a patient in need thereof a therapeutically effective amount of a compound of the formula (I)...
Search relevance: 174.89 | Views last month: 0 -
Background STAT3 phosphorylation is associated with the neoplastic state in many types of cancer, including prostate cancer. We investigated the role of IL-6 signaling and...
Search relevance: 131.27 | Views last month: 0 -
The dataset contains the number (volume) for 11 types of cancer (bladder, breast, brain, colon, esophagus, liver, lung, pancreas, prostate, rectum, and stomach) surgeries performed in California...
Search relevance: 122.81 | Views last month: 0 -
Background Antagonistic analogues of GnRH for the treatment of prostate cancer may be used clinically in persons for whom return to fertility after such treatment is important or...
Search relevance: 104.01 | Views last month: 2 -
Backgroud Bone mineral density (BMD) is a marker of long-term estrogen exposure. BMD measurement has been used in this context to investigate the association of estrogen with breast...
Search relevance: 90.47 | Views last month: 3 -
The invention relates to the use of arsenic trioxide to treat a solid tumor selected from the group consisting of breast, colon, ovarian, renal, bladder, prostate and lung cancer.
Search relevance: 76.51 | Views last month: 0 -
Methods for the use of Pin1 as a marker of abnormal cell growth are disclosed. In one embodiment, the method includes detecting a level of Pin1 to stage an abnormal cell growth, such as breast or...
Search relevance: 76.25 | Views last month: 0 -
XOFIGO (radium Ra 223 dichloride) is an intravenous injection manufactured by Bayer HealthCare Pharmaceuticals Inc. It's a radioactive alpha-particle emitting agent used to treat prostate cancer...
Search relevance: 76.22 | Views last month: 0 -
Abiraterone Acetate is a prescription oral tablet with 250 mg of the active ingredient, used to treat metastatic castration-resistant prostate cancer in men. It's a generic version manufactured by...
Search relevance: 70.45 | Views last month: 0 -
Background Several Retinoic Acid Receptors (RAR) agonists have therapeutic activity against a variety of cancer types; however, unacceptable toxicity profiles have hindered the...
Search relevance: 70.03 | Views last month: 2 -
Background The contribution of BRCA1 and BRCA2 to the incidence of male breast cancer (MBC) in the United Kingdom is not known, and the importance of these genes in the increased risk of...
Search relevance: 69.76 | Views last month: 3 -
The invention provides isolated anti-prostate stem cell antigen (PSCA) antibodies that internalize upon binding to PSCA on a mammalian in vivo. The invention also encompasses compositions...
Search relevance: 69.20 | Views last month: 0 -
Background A study for pain relief therapy with 188Re-HEDP was done in patients with bone metastases secondary to breast and prostate cancer. Materials and...
Search relevance: 61.00 | Views last month: 0 -
Background Breast cancer is hormone related, as are cancers of the endometrium, ovary, and prostate. Several studies have suggested that higher extracellular levels of androgens are...
Search relevance: 60.42 | Views last month: 0 -
Background In addition to endogenous opioids, a number of peptide sequences, derived from endogenous (hemorphins, alphaS1-casomorphin), and exogenous proteins (casomorphins, exorphins)...
Search relevance: 59.40 | Views last month: 1 -
Background In sporadic ovarian cancer, we have previously reported allele loss at D6S193 (62%) on chromosome 6q27, which suggested the presence of a putative tumour suppressor gene....
Search relevance: 57.39 | Views last month: 0
