Found 21 datasets matching "protein-families".
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A genome-wide analysis was carried out on patterns of the classified polytopic membrane protein families, and the distribution of conserved amino acids and motifs in the transmembrane helix...
Search relevance: 161.06 | Views last month: 0 -
Background: Protein fold recognition using sequence profile searches frequently allows prediction of the structure and biochemical mechanisms of proteins with an important biological...
Search relevance: 135.06 | Views last month: 0 -
VIDA is a new virus database that organizes open reading frames (ORFs) from partial and complete genomic sequences from animal viruses. Currently VIDA includes all sequences from GenBank for...
Search relevance: 113.34 | Views last month: 0 -
Background The Master Catalog is a collection of evolutionary families, including multiple sequence alignments, phylogenetic trees and reconstructed ancestral sequences, for all...
Search relevance: 54.30 | Views last month: 2 -
Background: Uracil DNA glycosylases (UDGs) are major repair enzymes that protect DNA from mutational damage caused by uracil incorporated as a result of a polymerase error or deamination...
Search relevance: 51.25 | Views last month: 0 -
The sequencing of genomes provides us with an inventory of the 'molecular parts' in nature, such as protein families and folds, and their functions in living organisms. The genomic occurrence of...
Search relevance: 50.65 | Views last month: 0 -
Background Current evidence suggests that lepidopteran baculoviruses may be divided into two phylogenetic groups based on their envelope fusion proteins. One group utilizes gp64, a low...
Search relevance: 49.86 | Views last month: 0 -
Background: Cohesin is a macromolecular complex that links sister chromatids together at the metaphase plate during mitosis. The links are formed during DNA replication and destroyed...
Search relevance: 46.05 | Views last month: 0 -
Background The yeast yCCR4 factor belongs to the CCR4-NOT transcriptional regulatory complex, in which it interacts, through its leucine-rich repeat (LRR) motif with yPOP2. Recently,...
Search relevance: 42.39 | Views last month: 0 -
Background Annotations of completely sequenced genomes reveal that nearly half of the genes identified are of unknown function, and that some belong to uncharacterized gene families. To...
Search relevance: 41.01 | Views last month: 0 -
Background Leucine-rich repeats are one of the more common modules found in proteins. The leucine-rich repeat consensus motif is LxxLxLxxNxLxxLxxLxxLxx- where the first 11–12 residues...
Search relevance: 40.31 | Views last month: 0 -
Background Recent studies of viral entry proteins from influenza, measles, human immunodeficiency virus, type 1 (HIV-1), and Ebola virus have shown, first with molecular modeling, and...
Search relevance: 40.22 | Views last month: 0 -
Background Prior to this report, members of the inward rectifier family, or Kir, have been found only in eukaryotes. Like most K+ channels, the pore-forming part of the protein is formed...
Search relevance: 39.95 | Views last month: 0 -
Background Since contradictory results have been reported, we reanalysed the 77C→G transition in exon 4 of the protein-tyrosine phosphatase receptor-type C (PTPRC also known as CD45) in...
Search relevance: 39.52 | Views last month: 0 -
Background The genome of Mycobacterium tuberculosis H37Rv has five copies of a cluster of genes known as the ESAT-6 loci. These clusters contain members of the CFP-10 (lhp) and ESAT-6...
Search relevance: 38.73 | Views last month: 0 -
Background The DNA single-strand annealing proteins (SSAPs), such as RecT, Redβ, ERF and Rad52, function in RecA-dependent and RecA-independent DNA recombination pathways. Recently, they...
Search relevance: 38.00 | Views last month: 0 -
Background The availability of multiple complete genome sequences from diverse taxa prompts the development of new phylogenetic approaches, which attempt to incorporate information...
Search relevance: 37.01 | Views last month: 2 -
Background Congenital fibrosis of the extraocular muscles type 1 (CFEOM1) is an autosomal dominant eye movement disorder linked to the pericentromere of chromosome 12 (12p11.2 - q12)....
Search relevance: 33.38 | Views last month: 0 -
Background: Sodium bicarbonate cotransporter (NBC) genes encode proteins that execute coupled Na+ and HCO3- transport across epithelial cell membranes. We report the discovery,...
Search relevance: 30.58 | Views last month: 0 -
Background Viral DNA-binding proteins have served as good models to study the biochemistry of transcription regulation and chromatin dynamics. Computational analysis of viral DNA-binding...
Search relevance: 29.35 | Views last month: 0
