Found 33 datasets matching "protein-synthesis".
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Background Activation of human resting T lymphocytes results in an immediate increase in protein synthesis. The increase in protein synthesis after 16–24 h has been linked to the...
Search relevance: 206.56 | Views last month: 0 -
Background A number of transcription factors coordinate differentiation by simultaneously regulating gene expression and cell proliferation. CCAAT/enhancer binding protein alpha (C/EBPα)...
Search relevance: 100.31 | Views last month: 0 -
Hepatitis C virus (HCV) is an important human pathogen that affects ∼100 million people worldwide. Its RNA genome codes for a polyprotein, which is cleaved by viral and cellular proteases to...
Search relevance: 96.41 | Views last month: 0 -
Background Setting of graded levels of a protein for in vivo studies by controlled gene expression has inconveniences, and we here explore the use of the t-degron technique instead. ...
Search relevance: 54.53 | Views last month: 0 -
Ciclopirox is a prescription antifungal shampoo used topically to treat fungal infections of the scalp, such as seborrheic dermatitis. It works by inhibiting protein synthesis in fungi....
Search relevance: 54.30 | Views last month: 0 -
AMONDYS 45 (casimersen) is an intravenous solution used to treat Duchenne muscular dystrophy in patients with a specific genetic mutation. It works as an antisense oligonucleotide to increase...
Search relevance: 53.32 | Views last month: 0 -
TROPHAMINE is an intravenous amino acid solution used for parenteral nutrition to provide essential and non-essential amino acids like leucine, isoleucine, and valine. It's administered by...
Search relevance: 53.02 | Views last month: 0 -
This dataset contains data supporting the paper: DeCrappeo, N.M., DeLorenze, E.J., Giguere, A.T., Pyke, D.A., and Bottomley, P.J. Fungal and bacterial contributions to nitrogen cycling in...
Search relevance: 52.81 | Views last month: 0 -
Dedication This article is dedicated to the memory of Sue Kim Hanson, a graduate student in the department of Pathology and Laboratory Medicine at Boston University School of Medicine,...
Search relevance: 52.21 | Views last month: 1 -
Dactinomycin is a prescription injectable drug, available as a lyophilized powder for intravenous use. Manufactured by Meitheal Pharmaceuticals Inc., it contains 0.5 mg of dactinomycin per vial...
Search relevance: 52.15 | Views last month: 0 -
Background Reversible protein phosphorylation is relatively unexplored in the intracellular protozoa of the Apicomplexa family that includes the genus Plasmodium, to which belong the...
Search relevance: 51.53 | Views last month: 0 -
Background In addition to immune cells, many other cell types are known to produce cytokines. Cultured normal mouse gallbladder epithelial cells, used as a model system for gallbladder...
Search relevance: 50.12 | Views last month: 0 -
Background Mutations in the fibrillin -1 gene (FBN1) cause Marfan syndrome (MFS), an autosomal dominant multi-system connective tissue disorder. The 200 different mutations reported in...
Search relevance: 49.47 | Views last month: 0 -
Background Soluble guanylyl cyclase (sGC) is the main receptor for nitric oxide (NO) when the latter is produced at low concentrations. This enzyme exists mainly as a heterodimer...
Search relevance: 48.28 | Views last month: 0 -
Background Wnt signaling is implicated in many developmental decisions, including stem cell control, as well as in cancer. There are relatively few target genes known of the Wnt...
Search relevance: 47.73 | Views last month: 0 -
Do we need clinical trials to test the ability of transdermal HRT to prevent coronary heart disease?
Postmenopausal hormone replacement therapy (HRT) with oral oestrogen was predicted to reduce coronary heart disease (CHD) risk by 50%. Randomized controlled trials show no such benefit, however,...
Search relevance: 46.05 | Views last month: 0 -
Datasets used in ORD-023408: A Gene Expression Biomarker Identifies Chemicals and Other Factors That Modulate Sterol Regulatory Element Binding Protein (SREBP) Highlighting Differences in Targeted...
Search relevance: 44.91 | Views last month: 0 -
Datasets used in ORD-023413: Frequent Modulation of the Sterol Regulatory Element Binding Protein (SREBP) by Chemical Exposure in the Livers of Rats. This dataset is associated with the...
Search relevance: 44.54 | Views last month: 1 -
Background Methylthioadenosine, the main by-product of spermidine synthesis, is degraded in Bacillus subtilis as adenine and methylthioribose. The latter is an excellent sulfur source...
Search relevance: 44.42 | Views last month: 0 -
Background A collection of over 20,000 Salmonella typhimurium LT2 mutants, sealed for four decades in agar stabs, is a unique resource for study of genetic and evolutionary changes....
Search relevance: 42.64 | Views last month: 0
