Found 23 datasets matching "pulmonary-inflammation".
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We have previously shown that neuroendocrine activation leading to increased circulating stress hormones was necessary for mediating ozone-induced lung injury and inflammation since adrenalectomy...
Search relevance: 148.41 | Views last month: 1 -
Interleukin-5 is produced by a number of cell types, and is responsible for the maturation and release of eosinophils in the bone marrow. In humans, interleukin-5 is a very selective cytokine as a...
Search relevance: 130.87 | Views last month: 0 -
Many pulmonary diseases preferentially affect the large airways or the alveoli. Although the mechanisms are often particular to each disease process, site-specific differences in leukocyte...
Search relevance: 128.12 | Views last month: 0 -
A recent review article suggested that idiopathic pulmonary fibrosis (IPF) is a disease that is associated more with abnormal wound healing than with inflammation. Data derived from transgenic and...
Search relevance: 121.30 | Views last month: 0 -
Pulmonary surfactant is a unique mixture of lipids and surfactant-specific proteins that covers the entire alveolar surface of the lungs. Surfactant is not restricted to the alveolar compartment;...
Search relevance: 115.56 | Views last month: 1 -
Phosphoinositide 3-kinases (PI-3Ks) are enzymes that generate lipid second messenger molecules, resulting in the activation of multiple intracellular signalling cascades. These events regulate a...
Search relevance: 108.72 | Views last month: 0 -
Idiopathic pulmonary fibrosis is a chronic and usually progressive lung disorder of unknown etiology. A growing body of evidence suggests that, in contrast to other interstitial lung diseases, IPF...
Search relevance: 70.16 | Views last month: 0 -
This paper reviews hypotheses about roles of angiogenesis in the pathogenesis of inflammatory disease in two organs, the synovial joint and the lung. Neovascularisation is a fundamental process...
Search relevance: 69.92 | Views last month: 0 -
Background Bronchopulmonary manifestations of Crohn disease have been rarely described in children, including both subclinical pulmonary involvement and severe lung disease. ...
Search relevance: 67.12 | Views last month: 0 -
Wixela Inhub is a prescription inhaler combining fluticasone propionate (a corticosteroid to reduce inflammation) and salmeterol (a long-acting bronchodilator to open airways). It's used to treat...
Search relevance: 66.80 | Views last month: 0 -
This data set pertains to the manuscript "Exacerbation of ozone-induced pulmonary and systemic effects by 2-adrenergic and/or glucocorticoid agonist/s". It shows the raw data for each figure in...
Search relevance: 66.58 | Views last month: 0 -
This data set is an excel file pertaining to the study that examined ozone-induced systemic and pulmonary effects in rats that underwent SHAM surgery (control), adrenal demedullation or total...
Search relevance: 64.41 | Views last month: 0 -
Background: Recent investigations have shown that leukocyte activation is involved in the pathogenesis of ventilator-associated lung injury. This study was designed to investigate...
Search relevance: 61.60 | Views last month: 0 -
The program at this year's American Thoracic Society international conference included over 300 scientific and clinical symposia. In this report I have reviewed the data presented on two important...
Search relevance: 60.07 | Views last month: 0 -
Objective: Inhalation of ozone activates central sympathetic-adrenal-medullary and hypothalamic-pituitary-adrenal stress axes. While airway neural networks are known to communicate noxious stimuli...
Search relevance: 58.16 | Views last month: 1 -
Endothelin-1 (ET-1) is a 21 amino acid peptide with diverse biological activity that has been implicated in numerous diseases. ET-1 is a potent mitogen regulator of smooth muscle tone, and...
Search relevance: 57.56 | Views last month: 0 -
The importance of balanced pro-inflammatory and anti-inflammatory mechanisms in diffuse lung disease
The lung responds to a variety of insults in a remarkably consistent fashion but with inconsistent outcomes that vary from complete resolution and return to normal to the destruction of normal...
Search relevance: 53.14 | Views last month: 1 -
Surfactant protein-D (SP-D) participates in the innate response to inhaled microorganisms and organic antigens, and contributes to immune and inflammatory regulation within the lung. SP-D is...
Search relevance: 53.09 | Views last month: 1 -
The dataset consists of 2 revised files. The excel file shows all of the individual data used in calculation of the tables and figures. Each table and figure has data stored on a separate tab of...
Search relevance: 51.85 | Views last month: 0 -
In this study, we investigated effects of inhaled ozone exposure and high-cholesterol diet (HCD) in healthy Wistar and Wistar-derived Goto-Kakizaki (GK) rats, a non-obese model of type 2 diabetes....
Search relevance: 49.77 | Views last month: 1
