Found 21 datasets matching "sepsis-treatment".
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Introduction The administration of antithrombin III (ATIII) is useful in patients with congenital deficiency, but evidence for the other therapeutic indications of this drug is still...
Search relevance: 107.44 | Views last month: 0 -
Corticosteroid treatment of severe sepsis has been one of the most controversial clinical issues in critical care. In fact, few agents can claim to have been evaluated in scores of studies...
Search relevance: 105.47 | Views last month: 1 -
Part of Stephan Jakob's exhaustive review paper in the present issue of Critical Care deals with the notion that intestinal cellular energetics are deranged in sepsis, in terms not only of...
Search relevance: 70.12 | Views last month: 0 -
Introduction Treatment of sepsis is aimed at increasing both the duration and quality of survival. A long-term focus on quality of life (QoL) in clinical trial evaluations of sepsis care...
Search relevance: 67.53 | Views last month: 1 -
This dataset provides the Emergency Department ratio of encounters and treatment stations to represent the ED Burden. Smaller ratios indicate fewer ED visits per available treatment station and...
Search relevance: 62.02 | Views last month: 367 -
Introduction Treatment of patients with severe sepsis with agents antagonising the effects of C5a has been proposed based on beneficial effects in animal experiments and in vitro studies...
Search relevance: 59.44 | Views last month: 0 -
Introduction In this prospective, randomized controlled study, we aimed to evaluate the effect of IgM-enriched immunoglobulin treatment on progression of organ failure and septic shock...
Search relevance: 57.59 | Views last month: 0 -
Great advances have been made in describing the intracellular pathways and genes that are activated by bacterial products. New definitions and therapies for sepsis will be based on such cellular...
Search relevance: 54.13 | Views last month: 2 -
A monoacyl semicarbazide of the general formula (I) nor a pharmaceutically acceptable salt or ester thereof, is capable of selectively inhibiting dipeptidyl-peptidase I (DPP-I), also known as...
Search relevance: 51.91 | Views last month: 1 -
Introduction: Clinically useful predictions of end-organ function and failure in severe sepsis may be possible through analyzing the interactions among demographics, physiologic...
Search relevance: 50.76 | Views last month: 1 -
Background: Nitric oxide (NO) production following bacterial infection may play a physiological role in the host defense mechanism due to its antimicrobial activity. However, excess...
Search relevance: 49.90 | Views last month: 0 -
Several studies indicate that organ failure is the leading cause of death in surgical patients. An excessive inflammatory response followed by a dramatic paralysis of cell-mediated immunity...
Search relevance: 48.46 | Views last month: 1 -
The present review discusses the hemodynamic effects of hypertonic saline in experimental shock and in patients with sepsis. We comment on the mechanisms of action of hypertonic saline, calling...
Search relevance: 47.25 | Views last month: 1 -
Introduction The aim of the study was to assess the prognostic importance of basal cortisol concentrations and cortisol response to corticotropin, and to determine the effects of...
Search relevance: 47.25 | Views last month: 0 -
The Congress took place at the northernmost academic center in the world, in the state-of-the art Tromso University Hospital. There were over 500 participants, mainly from Scandinavian countries,...
Search relevance: 46.16 | Views last month: 0 -
The 21st International Symposium on Intensive Care and Emergency Medicine was dominated by the results of recent clinical trials in sepsis and acute respiratory distress syndrome (ARDS). The...
Search relevance: 45.60 | Views last month: 0 -
The effect of dietary lead (Pb) on the murine intestinal microbiome was explored to determine if there was an association between microflora modulation and Pb source. Mice were treated with...
Search relevance: 43.17 | Views last month: 0 -
Background In addition to immune cells, many other cell types are known to produce cytokines. Cultured normal mouse gallbladder epithelial cells, used as a model system for gallbladder...
Search relevance: 40.86 | Views last month: 0 -
Background: Recent prospective controlled trials of induced moderate hypothermia (32⌓34°C) for relatively short periods (24⌓48 h) in patients with severe head injury have suggested...
Search relevance: 39.38 | Views last month: 1 -
Background: We studied the incidence of withholding or withdrawing therapeutic measures in intensive care unit (ICU) patients, as well as the possible implications of sepsis-related...
Search relevance: 35.76 | Views last month: 2