Found 36 datasets matching "sequence-similarity".
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Background In a variant of the standard PCR reaction termed bridging, or jumping, PCR the primer-bound sequences are originally on separate template molecules. Bridging can occur if, and...
Search relevance: 113.61 | Views last month: 0 -
A collection of Reference Sequence (RefSeq) proteins, from the complete genomes of prokaryotes, plasmids, and organelles, that have been grouped and annotated based on sequence similarity and...
Search relevance: 65.56 | Views last month: 0 -
Constraint-Based Multiple Alignment Tool (COBALT) is a protein multiple sequence alignment tool that finds a collection of pairwise constraints derived from conserved domain database, protein...
Search relevance: 64.23 | Views last month: 0 -
VIDA is a new virus database that organizes open reading frames (ORFs) from partial and complete genomic sequences from animal viruses. Currently VIDA includes all sequences from GenBank for...
Search relevance: 60.48 | Views last month: 0 -
Publicly available genetic sequence data were searched for human sequences that potentially represent protein kinases, important players in virtually every signaling pathway. After removal of...
Search relevance: 58.05 | Views last month: 2 -
Background A partial cDNA clone from dog thyroid presenting a very significant similarity with an uncharacterized mouse EST sequence was isolated fortuitously. We report here the...
Search relevance: 57.08 | Views last month: 0 -
Background The mammalian olfactory apparatus is able to recognize and distinguish thousands of structurally diverse volatile chemicals. This chemosensory function is mediated by a very...
Search relevance: 54.58 | Views last month: 0 -
The sequenceMiner was developed to address the problem of detecting and describing anomalies in large sets of high-dimensional symbol sequences. sequenceMiner works by performing unsupervised...
Search relevance: 53.61 | Views last month: 0 -
We present a set of novel algorithms which we call sequenceMiner that detect and characterize anomalies in large sets of high-dimensional symbol sequences that arise from recordings of switch...
Search relevance: 53.55 | Views last month: 0 -
Background Microorganisms inhabiting subterranean oil fields have recently attracted much attention. Since intact groundwater can easily be obtained from the bottom of underground...
Search relevance: 51.92 | Views last month: 0 -
Background Prior to this report, members of the inward rectifier family, or Kir, have been found only in eukaryotes. Like most K+ channels, the pore-forming part of the protein is formed...
Search relevance: 49.89 | Views last month: 0 -
Background: Uracil DNA glycosylases (UDGs) are major repair enzymes that protect DNA from mutational damage caused by uracil incorporated as a result of a polymerase error or deamination...
Search relevance: 48.29 | Views last month: 0 -
Background Leucine-rich repeats are one of the more common modules found in proteins. The leucine-rich repeat consensus motif is LxxLxLxxNxLxxLxxLxxLxx- where the first 11–12 residues...
Search relevance: 47.26 | Views last month: 0 -
Arteri-, corona-, toro- and roniviruses are evolutionarily related positive-strand RNA viruses, united in the order Nidovirales. The best studied nidoviruses, the corona- and arteriviruses, employ...
Search relevance: 47.16 | Views last month: 1 -
Background Identification of co-regulated genes is essential for elucidating transcriptional regulatory networks and the function of uncharacterized genes. Although co-regulated genes...
Search relevance: 44.78 | Views last month: 0 -
Background The S. cerevisiae origin recognition complex binds to the ARS consensus sequence in an ATP dependent fashion. Recently, the yeast Cdc6 has been reported to have DNA binding...
Search relevance: 44.76 | Views last month: 0 -
Background Based on sequence similarity, the superfamily of G protein-coupled receptors (GPRs) can be subdivided into several subfamilies, the members of which often share similar...
Search relevance: 44.26 | Views last month: 0 -
Background In mammals, L-threonine is an indispensable amino acid. The conversion of L-threonine to glycine occurs through a two-step biochemical pathway involving the enzymes...
Search relevance: 44.21 | Views last month: 0
