Found 59 datasets matching "signaling pathways".
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Differential genomic effects on signaling pathways by two different CeO2 nanoparticles in HepG2 cells. This dataset is associated with the following publication: Thai , S., K. Wallace , C. Jones...
Search relevance: 224.28 | Views last month: 2 -
Background Bruton's tyrosine kinase (Btk) is essential for B cell development and function. Mutations of Btk elicit X-linked agammaglobulinemia in humans and X-linked immunodeficiency in...
Search relevance: 149.61 | Views last month: 0 -
Signaling pathways from IPA: canonical pathways obtained by uploading differentially expressed genes onto IPA to get the corresponding pathways altered by the chemicals. Figure 4 ABCDHILM ROS...
Search relevance: 104.87 | Views last month: 1 -
Matrix metalloproteinase (MMP)-1, MMP-8 and MMP-13 are interstitial collagenases that degrade type II collagen in cartilage; this is a committed step in the progression of rheumatoid arthritis and...
Search relevance: 77.49 | Views last month: 0 -
Background The serum response element (SRE) in the c-fos promoter is a convergence point for several signaling pathways that regulate induction of the c-fos gene. Many transcription...
Search relevance: 68.44 | Views last month: 0 -
Recent advances in methodology have made phosphopeptide analysis a tractable problem for many proteomicists. There are now a wide variety of robust and inexpensive enrichment strategies to...
Search relevance: 64.38 | Views last month: 0 -
Among the physiological consequences of extended spaceflight are loss of skeletal muscle and bone mass. One signaling pathway that plays an important role in maintaining muscle and bone...
Search relevance: 62.44 | Views last month: 1 -
A cell-culture model was used to establish a profile of gene expression during the effector phase of ceramide-mediated cell death. Of the 239 genes that met the criteria for differential...
Search relevance: 61.64 | Views last month: 0 -
Cytokines play a critical role in the normal development and function of the immune system. On the other hand, many rheumatologic diseases are characterized by poorly controlled responses to...
Search relevance: 60.86 | Views last month: 0 -
Background STAT3 phosphorylation is associated with the neoplastic state in many types of cancer, including prostate cancer. We investigated the role of IL-6 signaling and...
Search relevance: 60.28 | Views last month: 0 -
The synovial tissue in rheumatoid arthritis (RA) patients is enriched with mature antigen presenting cells (APCs) and many T lymphocytes. Interactions between APCs and T cells are essential for...
Search relevance: 58.11 | Views last month: 0 -
Dataset for 'Effects of multi-walled carbon nanotubes on gene and microRNA expression in human hepatocarcinoma HepG2 cells' by Sheau-Fung Thai et al., accepted by Materials Express. For the data...
Search relevance: 57.48 | Views last month: 0 -
IL-6 is a multifunctional cytokine produced by lymphoid and nonlymphoid cells; it regulates immune responses, acute-phase reactions, and inflammation. IL-6 signaling is mediated exclusively by the...
Search relevance: 57.07 | Views last month: 0 -
The functional genomic response of developing embryonic submandibular glands to NF-kappaB inhibition
Background The proper balance between epithelial cell proliferation, quiescence, and apoptosis during development is mediated by the specific temporal and spatial appearance of...
Search relevance: 56.25 | Views last month: 1 -
Autoantibodies present in the serum of patients with a variety of inflammatory diseases have proven useful as diagnostic markers and as probes with which to elucidate biochemical and signaling...
Search relevance: 54.98 | Views last month: 1 -
Adaptation of humans in low gravity conditions is a matter of utmost importance when efforts are on to a gigantic leap in human space expeditions for tourism and formation of space colonies. In...
Search relevance: 54.94 | Views last month: 0 -
['Plants are primary producers of food and oxygen on Earth and will likewise be indispensable to the establishment of large-scale sustainable ecosystems and human survival in space. To contribute...
Search relevance: 53.14 | Views last month: 0 -
canonical pathways for each concentration of nano Cu and CuCl2 after upload the DEG lists of each concentration to Ingenuity Pathway Analysis
Search relevance: 52.98 | Views last month: 0 -
Data collected during the comparison of ozone responsiveness in primary bronchial epithelial cells from a range of distinct donors. This dataset is associated with the following...
Search relevance: 52.94 | Views last month: 0 -
Publicly available genetic sequence data were searched for human sequences that potentially represent protein kinases, important players in virtually every signaling pathway. After removal of...
Search relevance: 52.90 | Views last month: 2
