Found 2 datasets matching "smoothened-antagonists".
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Background The Hedgehog (Hh) signaling pathway is vital to animal development as it mediates the differentiation of multiple cell types during embryogenesis. In adults, Hh signaling can...
Search relevance: 182.90 | Views last month: 0 -
Small-molecule antagonists of Hedgehog-pathway signaling, such as cyclopamine, have been known for some time. Now, small-molecule agonists of the Hedgehog pathway have also been identified. The...
Search relevance: 108.82 | Views last month: 0
