Found 15 datasets matching "statin".
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Statins reduce mortality of patients with coronary artery disease (CAD). However, by protocol, trials have excluded patients with chronic heart failure. Since the prevalent etiology of heart...
Search relevance: 99.53 | Views last month: 2 -
Large scale clinical trials demonstrate significant reductions in cardiovascular event rates with statin therapy. The observed benefit of statin therapy, however, may be larger in these trials...
Search relevance: 83.95 | Views last month: 1 -
The importance of low-density lipoprotein (LDL) control in the management of patients at high risk of cardiovascular events is unquestionable. The major statin trials have shown that the benefits...
Search relevance: 79.66 | Views last month: 1 -
The Myocardial Ischemia Reduction with Aggressive Cholesterol Lowering (MIRACL) study was the first trial to assess whether statins might be of clinical benefit in those with recently unstable...
Search relevance: 70.89 | Views last month: 3 -
Rosuvastatin is a generic statin medication that helps lower cholesterol and triglyceride levels in the blood, reducing the risk of heart disease and stroke. Manufactured by Macleods...
Search relevance: 43.48 | Views last month: 0 -
Three clinical trials have recently focused on the benefits of lipid-regulating therapy in populations with normocholesterolaemia and low high-density lipoprotein (HDL)-cholesterol. Two secondary...
Search relevance: 41.72 | Views last month: 1 -
The greater dynamic range of testosterone production in a highly purified rat Leydig cell assay permitted the detection of chemical induced inhibition that was not detected by the high throughput...
Search relevance: 40.22 | Views last month: 1 -
The treatment of patients with coronary artery disease continues to evolve; all three strategies – medical therapy, surgical revascularization, and percutaneous coronary intervention – have...
Search relevance: 35.71 | Views last month: 0 -
Recent studies have proposed an association between hyperlipidemia and venous thromboembolism (VTE). We review the epidemiological evidence linking dyslipidemia with VTE and examine several...
Search relevance: 31.87 | Views last month: 0 -
The use of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) to reduce serum cholesterol is well described. However, the recent finding that statins have direct effects on bone...
Search relevance: 31.33 | Views last month: 0 -
Cerivastatin was recently withdrawn from the market because of 52 deaths attributed to drug-related rhabdomyolysis that lead to kidney failure. The risk was found to be higher among patients who...
Search relevance: 30.96 | Views last month: 0 -
Treatment to prevent progression of heart failure has been targeted to reverse the consequences of heart failure and to a lesser extent the cause – the atherosclerotic plaque itself. Less than 50%...
Search relevance: 30.70 | Views last month: 2 -
Inhibitors of the 3-hydroxy-3-methylglutaryl coenzyme A reductase enzyme have recently been shown to stimulate bone formation in rodents both in vitro and in vivo. In bone cells, these inhibitors...
Search relevance: 30.34 | Views last month: 0 -
Background PROSPER was designed to investigate the benefits of treatment with pravastatin in elderly patients for whom a typical doctor might consider the prescription of statin therapy...
Search relevance: 26.77 | Views last month: 0 -
The database provides information on prescribed amounts, levels detected in aquatic environments, chemical structure, molecular weight, octanol-water partition coefficients, water solubility,...
Search relevance: 15.79 | Views last month: 1
