Found 37 datasets matching "steroid".
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Introduction The aim of the study was to assess the prognostic importance of basal cortisol concentrations and cortisol response to corticotropin, and to determine the effects of...
Search relevance: 152.74 | Views last month: 0 -
A novel nuclear receptor, termed the steroid and xenobiotic receptor (SXR), a broad-specificity sensing receptor that is a novel branch of the nuclear receptor superfamily, has been discovered....
Search relevance: 102.50 | Views last month: 0 -
Dataset from Foster, M.J., et al., Evaluating structure-based activity in a high-throughput assay for steroid biosynthesis, Computational Toxicology, Vol 24, No. 100245, Nov 2022, DOI...
Search relevance: 101.00 | Views last month: 0 -
Liquid chromatography tandem mass spectrometry allows for the measurement of steroid hormone suites in the blubber of marine mammals. By combining this technology with remote biopsy collection,...
Search relevance: 80.24 | Views last month: 0 -
Background Changes in breast density are highly correlated with steroid hormone exposure. Materials and methods In a cross-sectional study of 396...
Search relevance: 73.95 | Views last month: 2 -
Background Breast cancer is hormone related, as are cancers of the endometrium, ovary, and prostate. Several studies have suggested that higher extracellular levels of androgens are...
Search relevance: 71.04 | Views last month: 0 -
Aromatase inhibition is one of the chemical modes of action of concern to EPA's Endocrine Disruptor Screening Program (EDSP). In vitro bioassays that can detect aromatase inhibition are part of...
Search relevance: 68.14 | Views last month: 1 -
Decision-making in the intensive care unit is often very difficult. Although we are encouraged to make evidence-based decisions, this may be difficult for a number of reasons. To begin with,...
Search relevance: 64.62 | Views last month: 0 -
The aim of this study was to investigate temporal changes in the hypothalamic-pituitary-gonadal axis of fathead minnow treated with the model androgen receptor (AR) antagonist, flutamide....
Search relevance: 42.54 | Views last month: 0 -
The occurrence of chemicals of emerging concern (CECs) and potential effects to aquatic biota in select tributaries of the St. Croix River in Minnesota and Wisconsin were measured. In 2011,...
Search relevance: 41.14 | Views last month: 0 -
Cardiovascular effects of vitamin D deficiency and pharmacological characterization of the role of TRPC6 in the effects. This dataset is associated with the following publication: Stratford, K.,...
Search relevance: 36.45 | Views last month: 0 -
Background In learning and memory tasks, requiring visual spatial memory (VSM), males exhibit higher performance levels compared to females (a difference attributed to sex steroid...
Search relevance: 35.24 | Views last month: 2 -
Corticosteroid treatment of severe sepsis has been one of the most controversial clinical issues in critical care. In fact, few agents can claim to have been evaluated in scores of studies...
Search relevance: 35.21 | Views last month: 1 -
Triclosan data from Hershberger experiment using castrated male rats. Data includes accessory sex tissue mean weights and thyroid gland weight following exposure to triclosan for 10 days both...
Search relevance: 34.11 | Views last month: 0 -
Glucocorticoids (GCs) are routinely used as anti-inflammatory drugs in the treatment of asthma. They act through binding to glucocorticoid receptor α (GRα), which represses numerous genes encoding...
Search relevance: 33.59 | Views last month: 0 -
The U.S. Geological Survey (USGS), in cooperation with the U.S. Fish and Wildlife Service (USFWS) and the U.S. Environmental Protection Agency (EPA), identified the occurrence of contaminants of...
Search relevance: 33.39 | Views last month: 0 -
The U.S. Geological Survey (USGS), in cooperation with the U.S. Fish and Wildlife Service (USFWS) and the U.S. Environmental Protection Agency (EPA), identified the occurrence of contaminants of...
Search relevance: 33.39 | Views last month: 0 -
Disruption of steroidogenesis by environmental chemicals can result in altered hormone levels causing adverse reproductive and developmental effects. A high-throughput assay using H295R human...
Search relevance: 33.21 | Views last month: 0 -
Background Recent reports have raised concerns that postnatal steroids may cause neuro-developmental impairment in preterm infants. This systematic review was performed with the...
Search relevance: 32.25 | Views last month: 3 -
It has become increasingly recognized that skeletal muscle dysfunction is common in patients with chronic obstructive pulmonary disease (COPD). Muscle strength and endurance are decreased, whereas...
Search relevance: 31.77 | Views last month: 1
