Found 47 datasets matching "target-genes".
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Background Wnt signaling is implicated in many developmental decisions, including stem cell control, as well as in cancer. There are relatively few target genes known of the Wnt...
Search relevance: 111.49 | Views last month: 0 -
Background: Homeotic genes are key developmental regulators that are highly conserved throughout evolution. Their encoded homeoproteins function as transcription factors to control a...
Search relevance: 55.99 | Views last month: 0 -
Background Suppression Subtractive Hybridization PCR (SSH PCR) is a sophisticated cDNA subtraction method to enrich and isolate differentially expressed genes. Despite its popularity,...
Search relevance: 50.74 | Views last month: 0 -
File contains raw data collected on body and organ weights of mice given PFBS and body burden of the chemical after intervals of several hours, as well as expression of liver candidate genes for...
Search relevance: 47.69 | Views last month: 1 -
Background Homeobox genes of the orthodenticle (otd)/Otx family have conserved roles in the embryogenesis of head and brain. Gene replacement experiments show that the Drosophila otd...
Search relevance: 47.37 | Views last month: 0 -
The hedgehog signalling pathway has been implicated in many different processes in fly and vertebrate development. It is now known that the hedgehog cascade is crucial for the patterning of the...
Search relevance: 44.71 | Views last month: 0 -
Background PCR amplification of target molecules involves sequence specific primers that flank the region to be amplified. While this technique is generally routine, its applicability...
Search relevance: 44.56 | Views last month: 0 -
se of archival resources has been limited to date by inconsistent methods for genomic profiling of degraded RNA from formalin-fixed paraffin-embedded (FFPE) samples. RNA-seq offers a novel way to...
Search relevance: 44.09 | Views last month: 1 -
It is not known to what extent glucocorticoid hormones cause their anti-inflammatory actions and their undesirable side effects by the same or different molecular mechanisms. Glucocorticoids...
Search relevance: 42.70 | Views last month: 0 -
Nebraska Prairie Study for Agricultural Antibiotic Resistance in Lincoln, Nebraska The inherent spatial heterogeneity and complexity of antibiotic resistant bacteria and antibiotic resistance (AR)...
Search relevance: 41.11 | Views last month: 0 -
Background The moss Physcomitrella patens is an attractive model system for plant biology and functional genome analysis. It shares many biological features with higher plants but has...
Search relevance: 37.93 | Views last month: 0 -
Background Gene expression profiling among different tissues is of paramount interest in various areas of biomedical research. We have developed a novel method (DADA, Digital Analysis of...
Search relevance: 37.04 | Views last month: 1 -
2014 Swine CAFO Study SE for Agricultural Antibiotic Resistance in Mississippi State, Mississippi The environmental influence of farm management in concentrated animal feeding operations (CAFO)...
Search relevance: 36.71 | Views last month: 0 -
Background Genomic instability has been reported at microsatellite tracts in few coding sequences. We have shown that the Bloom syndrome BLM gene may be a target of...
Search relevance: 36.52 | Views last month: 1 -
Mitochondrial DNA-depleted human skin fibroblasts (HSF rho0) with suppressed oxidative phosphorylation were characterized by significant changes in the expression of 2100 nuclear genes encoding...
Search relevance: 36.46 | Views last month: 0 -
Manual annotation at the i5k Workspace@NAL (https://i5k.nal.usda.gov) is the review and improvement of gene models derived from computational gene prediction. Community curators compare an...
Search relevance: 36.28 | Views last month: 2 -
Background The power of DNA microarrays derives from their ability to monitor the expression levels of many genes in parallel. One of the limitations of such powerful analytical tools is...
Search relevance: 35.88 | Views last month: 0 -
Background Treatment of mouse F9 embryonal carcinoma cells with all-trans retinoic acid (T-RA) induces differentiation into primitive endodermal type cells. Differentiation requires the...
Search relevance: 35.86 | Views last month: 0 -
Background A model-based analysis of oligonucleotide expression arrays we developed previously uses a probe-sensitivity index to capture the response characteristic of a specific probe...
Search relevance: 35.86 | Views last month: 0 -
[NOTE: PLEXdb is no longer available online. Oct 2019.] PLEXdb (Plant Expression Database) is a unified gene expression resource for plants and plant pathogens. PLEXdb is a genotype to phenotype,...
Search relevance: 35.06 | Views last month: 1