Found 12 datasets matching "therapeutic-trials".
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Randomized trials and observational studies, such as case-control studies, are often seen as opposing approaches. However, in many instances results obtained by different designs may complement...
Search relevance: 127.59 | Views last month: 3 -
The identification of angiogenic growth factors, such as vascular endothelial growth factor and fibroblast growth factor, has fueled interest in using such factors to induce therapeutic...
Search relevance: 63.35 | Views last month: 0 -
Background The evaluation of randomized trials for cancer screening involves special statistical considerations not found in therapeutic trials. Although some of these issues have been...
Search relevance: 59.62 | Views last month: 1 -
Early approaches to the development of oxygen carriers involved the use of stroma-free hemoglobin solutions. These solutions did not require blood typing or crossmatching and could be stored...
Search relevance: 56.19 | Views last month: 0 -
The fundamental methodological deficiency of megatrials is deliberate reduction of experimental control in order to maximize recruitment and compliance of subjects. Hence, typical megatrials...
Search relevance: 56.06 | Views last month: 0 -
Background The relative efficacy of antiemetics for the treatment of postoperative nausea and vomiting (PONV) is poorly understood. Methods ...
Search relevance: 53.36 | Views last month: 1 -
Interleukin-4 (IL-4) mediates important pro-inflammatory functions in asthma including induction of the IgE isotype switch, expression of vascular cell adhesion molecule-1 (VCAM-1), promotion of...
Search relevance: 51.25 | Views last month: 0 -
Background: Recent prospective controlled trials of induced moderate hypothermia (32⌓34°C) for relatively short periods (24⌓48 h) in patients with severe head injury have suggested...
Search relevance: 50.50 | Views last month: 1 -
Background Antibiotics are frequently prescribed for older adults who reside in long-term care facilities. A substantial proportion of antibiotic use in this setting is inappropriate....
Search relevance: 45.07 | Views last month: 0 -
Background Granuloma annulare is a granulomatous disease of unknown etiology. Various therapies have been tried in disseminated granuloma annulare (DGA), including corticosteroids,...
Search relevance: 41.40 | Views last month: 1 -
Introduction The administration of antithrombin III (ATIII) is useful in patients with congenital deficiency, but evidence for the other therapeutic indications of this drug is still...
Search relevance: 40.22 | Views last month: 0 -
Background It is not uncommon to observe circulating tumor antigen-specific T lymphocytes in cancer patients despite a lack of significant infiltration and destruction of their tumors....
Search relevance: 37.36 | Views last month: 0
