Found 6 datasets matching "topoisomerase-i".
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Background Two-hybrid screening for proteins that interact with the core domain of human topoisomerase I identified two novel proteins, BTBD1 and BTBD2, which share 80% amino acid...
Search relevance: 212.36 | Views last month: 0 -
The main manifestation of systemic sclerosis (SSc) is the overproduction of extracellular matrix, predominantly type I collagen. This study was undertaken to evaluate the effects of noncytotoxic...
Search relevance: 151.82 | Views last month: 1 -
Background In most organisms proper reductional chromosome segregation during meiosis I is strongly correlated with the presence of crossover recombination structures (chiasmata);...
Search relevance: 50.62 | Views last month: 0 -
Background Escherichia coli DNA topoisomerase I binds three Zn(II) with three tetracysteine motifs which, together with the 14 kDa C-terminal region, form a 30 kDa DNA binding domain (ZD...
Search relevance: 44.33 | Views last month: 0 -
Background As part of a study aimed at developing new pharmaceutical products from natural resources, the purpose of this research was twofold: (1) to fractionate crude extracts from the...
Search relevance: 40.92 | Views last month: 0 -
Background Elevated plasma counts of endothelial microparticles (MP) have been demonstrated in various diseases with a vascular injury component. We used flow cytometry to study the...
Search relevance: 35.38 | Views last month: 0
