Found 15 datasets matching "toxicity pathways".
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This dataset comprises one SigmaPlot 13 file containing measured survival data and survival data predicted from the model coefficients selected by the LASSO procedure. This dataset is associated...
Search relevance: 190.33 | Views last month: 0 -
Background: Chemical toxicity testing is being transformed by advances in biology and computer modeling, concerns over animal use and the thousands of environmental chemicals lacking toxicity...
Search relevance: 68.31 | Views last month: 6 -
The dataset include the following figures and tables: 1)Changes in protein expression of the 14 pathway regulators induced by Ni (II). 2)Hierarchical clustering of 12 differentially expressed or...
Search relevance: 50.95 | Views last month: 0 -
Background Maitotoxin (MTX) initiates cell death by sequentially activating 1) Ca2+ influx via non-selective cation channels, 2) uptake of vital dyes via formation of large pores, and 3)...
Search relevance: 48.88 | Views last month: 0 -
The data presented here support the application of the Stemina devTOXqP platform for predictive toxicology and further demonstrate its value in ToxCast as a novel resource that can generate...
Search relevance: 48.54 | Views last month: 0 -
Metals are used in primary producer metabolic pathways, such as photosynthesis and the acquisition of macronutrients nitrogen (N) and phosphorus (P), yet we often do not know their potential as...
Search relevance: 46.02 | Views last month: 0 -
In 2017 the Wisconsin DNR reported observation of a high incidence of fish with fin erosion in Newton Creek, which originates near the site of the Calumet (later Husky) oil refinery and flows...
Search relevance: 45.61 | Views last month: 3 -
Water-borne contaminants were monitored in 69 tributaries of the Laurentian Great Lakes in 2010 and 2014 using semipermeable membrane devices (SPMDs), and polar organic chemical integrative...
Search relevance: 44.20 | Views last month: 0 -
Chemical toxicity can arise from disruption of specific biomolecular functions or through more generalized cell stress and cytotoxicity-mediated processes. Here, concentration-dependent responses...
Search relevance: 36.33 | Views last month: 3 -
The microgravity environment aboard the International Space Station (ISS) provides a unique stressor that can help understand underlying cellular and molecular drivers of pathological changes...
Search relevance: 33.95 | Views last month: 0 -
Proportional response addition (Prop-RA), a model for predicting response from chemical mixture exposure, is demonstrated, and evaluated by statistically evaluating data on all possible binary...
Search relevance: 32.52 | Views last month: 1 -
Background: Trends in male reproductive health have been reported for increased rates of testicular germ cell tumors, low semen quality, cryptorchidism, and hypospadias, which have been associated...
Search relevance: 31.24 | Views last month: 3 -
Background: Chemicals in consumer products are a major contributor to human chemical co-exposures. Consumers purchase and use a wide variety of products containing potentially thousands of...
Search relevance: 31.20 | Views last month: 5 -
Avian botulism toxicity is a common cause of death to water and shore birds that live near or migrate through Lake Michigan. The botulism neuro-toxin type E (bontE) gene is responsible for the...
Search relevance: 18.95 | Views last month: 0
