Found 74 datasets matching "transcriptomics".
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Supplemental datafiles for journal article 'High-Throughput Transcriptomics Screen of ToxCast Chemicals in U-2 OS Cells'.
Search relevance: 128.81 | Views last month: 0 -
Supplementary data for "Comparison of whole transcriptome and targeted RNA sequencing for ecological high-throughput transcriptomics". This dataset is associated with the following...
Search relevance: 126.08 | Views last month: 12 -
Dataset for Harrill, J.A. et al., 'Signature Analysis of High-Throughput Transcriptomics Screening Data for Mechanistic Inference and Chemical Grouping' published in Toxicological Sciences,...
Search relevance: 120.97 | Views last month: 0 -
The present study describes pilot testing of a high throughput compatible transcriptomics assay with larval fathead minnows. One day post hatch fathead minnows were exposed to eleven different...
Search relevance: 119.41 | Views last month: 0 -
We screened 44 chemicals in MCF7 cells in concentration response and generated HTTr data using the TempO-Seq hWTv1 assay. First, we provide an outline of the quality of the HTTr data based on a...
Search relevance: 113.61 | Views last month: 0 -
We introduce a new high-throughput transcriptomics (HTTr) platform comprised of a collagen sandwich primary rat hepatocyte culture and the TempO-Seq assay for screening and prioritizing potential...
Search relevance: 110.73 | Views last month: 5 -
The construction of SRP consensus signatures sets was completed in three steps. First, we constructed consensus signatures by merging and pruning relevant gene sets from the MSigDB v7.1. Second,...
Search relevance: 108.75 | Views last month: 0 -
Dataset for Rogers, et al., 'High-Throughput Transcriptomics of Water Extracts Detects Reductions in Biological Activity with Water Treatment Processes', published in Environmental Science &...
Search relevance: 107.69 | Views last month: 0 -
Production of per- and polyfluoroalkyl substances (PFAS) has shifted from long-chain perfluoroalkyl acids to short-chain compounds and those with ether bonds in the carbon chain. Next-generation...
Search relevance: 89.74 | Views last month: 2 -
This dataset is a project file generated by BMDExpress 2.2 SW (Sciome, Research Triangle Park, NC). It contains gene expression data for livers of rats exposed to 4 chemicals (crude MCHM, neat...
Search relevance: 85.52 | Views last month: 1 -
Spaceflight presents a unique environment with complex stressors, including microgravity and radiation, that can influence plant physiology at molecular levels. Combining transcriptomics and...
Search relevance: 84.50 | Views last month: 0 -
The U.S. Tox21 Federal collaboration, which currently quantifies the biological effects of nearly 10,000 chemicals via quantitative high-throughput screening(qHTS) in in vitro model systems, is...
Search relevance: 81.31 | Views last month: 0 -
Whole transcriptomics dose response data is collected and storedthrough public facing Gene Expression Omnibus database. Raw collected viability/cytotoxicity data for each chemical are collected...
Search relevance: 78.13 | Views last month: 0 -
Mice were flown onboard STS-135 and returned to Earth for analysis. Cerebellums were collected within 3-4 hours of landing and snap frozen in liquid nitrogen. Samples were shipped to UCI Genomics...
Search relevance: 71.31 | Views last month: 0 -
In the Rodent Research Reference Mission (RRRM-2), forty female C57BL/6NTac mice were flown on the International Space Station. To assess differences in outcomes due to age, twenty 12 week-old and...
Search relevance: 70.22 | Views last month: 0 -
The objective of the Rodent Research-10 mission (RR-10) was to investigate how spaceflight affects the cellular and molecular mechanisms of normal bone tissue regeneration in space. To this end,...
Search relevance: 67.10 | Views last month: 0 -
Mice were flown onboard STS-135 and returned to Earth for analysis. Livers were collected within 3-4 hours of landing and snap frozen in liquid nitrogen. Samples were shipped to UCI Genomics High...
Search relevance: 65.55 | Views last month: 0 -
On Earth plants are constantly exposed to a gravitational field of 1G. Gravity affects a plant in every step of its development. Germinating seedlings orient their radicle and hypocotyl and...
Search relevance: 63.13 | Views last month: 0 -
This dataset contains files reconstructing single-cell data presented in 'Reference transcriptomics of porcine peripheral immune cells created through bulk and single-cell RNA sequencing' by...
Search relevance: 60.63 | Views last month: 0 -
Female C57BL/6CR mice were flown onboard STS-135 for 13 days and returned to Earth for analysis. Livers were collected within 3-4 hours of landing and snap frozen in liquid nitrogen. Liver tissue...
Search relevance: 59.47 | Views last month: 0
