Found 35 datasets matching "treatment-protocol-nucleic-acid-extraction-library-construction-nucleic-acid-sequencing".
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Previous spaceflight experiments using Bacillus subtilis have reported altered transcriptome profiles during spaceflight compared to matching ground samples. This study tried to replicate those...
Search relevance: 226.16 | Views last month: 0 -
The purpose of this project was to determine the effects of chronic exposure to unpredictable mild socio-environmental stressors during gestation on the TCR-beta repertoire of newborn mice.
Search relevance: 225.56 | Views last month: 0 -
Physical inactivity decreases the mechanical load on the skeleton which when prolonged leads to losses of muscle strength and bone mass in humans and most mammalian species. Hibernating mammals...
Search relevance: 223.58 | Views last month: 0 -
Adaptation of humans in low gravity conditions is a matter of utmost importance when efforts are on to a gigantic leap in human space expeditions for tourism and formation of space colonies. In...
Search relevance: 223.02 | Views last month: 0 -
Understanding plant adaptive responses to the space environment is a requisite for enabling space farming. Spaceflight produce deleterious effects on plant cells particularly affecting ribosome...
Search relevance: 222.45 | Views last month: 0 -
Previous spaceflight experiments using Bacillus subtilis have reported altered transcriptome profiles during spaceflight compared to matching ground samples. This study tried to replicate those...
Search relevance: 222.45 | Views last month: 0 -
['To reveal the potential mechanisms involved in the dysfunction of antiviral immune responses under simulated microgravity conditions, we investigated the transcriptional changes related to the...
Search relevance: 222.22 | Views last month: 0 -
Here in this study we systematically examined the patterns of DNA methylation and hydroxy-methylation with its functional implications in gene regulation for the cultured TK6 lymphoblastoid cells...
Search relevance: 221.79 | Views last month: 0 -
['Plants are primary producers of food and oxygen on Earth and will likewise be indispensable to the establishment of large-scale sustainable ecosystems and human survival in space. To contribute...
Search relevance: 221.46 | Views last month: 0 -
In the Rocket Science citizen science project Eruca sativa (salad rocket) seeds stored for six months on board of the International Space Station caused delayed crop establishment. Here we...
Search relevance: 220.94 | Views last month: 0 -
['Cancer-causing genome instability is a major concern during space travel due to exposure of astronauts to potent sources of high-linear energy transfer (LET) ionizing radiation. Hematopoietic...
Search relevance: 220.38 | Views last month: 0 -
['"Understanding physiologic reactions to weightlessness is an indispensable requirement for safe human space missions. While adaptations of human organ systems in response to weightlessness have...
Search relevance: 219.87 | Views last month: 0 -
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA work has shown both TGF xce...
Search relevance: 218.34 | Views last month: 0 -
Immune dysregulation is among the main adverse outcomes of spaceflight. Despite its crucial role in host protection effects on the human antibody repertoire are unknown. Consequently we examined...
Search relevance: 218.34 | Views last month: 0 -
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA work has shown both TGF xce...
Search relevance: 218.34 | Views last month: 0 -
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA work has shown both TGF xce...
Search relevance: 217.34 | Views last month: 0 -
Biological risks associated with space radiation and microgravity are major concerns for long-term space travel. Through a Systems Biology approach our previous NASA work has shown both TGF xce...
Search relevance: 216.71 | Views last month: 0 -
The response of plants to the spaceflight environment and microgravity is still not well understood although there has been an increased emphasis on this topic. Even less is known about plants ...
Search relevance: 216.71 | Views last month: 0 -
DNA methylation is a very important kind of epigenetic modification and participates in many biological functions. Although many previous studies have addressed various plant species the study of...
Search relevance: 216.20 | Views last month: 0 -
The purpose of the present study was to evaluate damage in brain and eye in a ground-based model for spaceflight which includes prolonged unloading and low-dose radiation. Low-dose/Low-dose-rate...
Search relevance: 215.90 | Views last month: 0