Found 32 datasets matching "tumor-growth".
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Background Functional antagonism between transforming growth factor beta (TGF-β) and hyaluronidase has been demonstrated. For example, testicular hyaluronidase PH-20 counteracts...
Search relevance: 113.61 | Views last month: 0 -
Background Phosphatidylinositol-3,4,5-triphosphate (PtdInsP3) signaling is elevated in many tumors due to loss of the tumor suppressor PTEN, and leads to constitutive activation of Akt,...
Search relevance: 110.62 | Views last month: 0 -
The present invention provides compositions and methods for increasing therapeutic gain in radiotherapy and chemotherapy for proliferating malignant or nonmalignant disease to produce high...
Search relevance: 66.62 | Views last month: 0 -
Irradiated hosts gave rise to significantly more Trp53 null mammary cancers that grew more rapidly than those in sham-irradiated mice and exhibited an immunosuppressive tumor microenvironment....
Search relevance: 65.26 | Views last month: 1 -
Background The tumor suppressor gene PTEN has been found mutated in many types of advanced tumors. When introduced into tumor cells that lack the wild-type allele of the gene, exogenous...
Search relevance: 64.51 | Views last month: 0 -
Background It is not uncommon to observe circulating tumor antigen-specific T lymphocytes in cancer patients despite a lack of significant infiltration and destruction of their tumors....
Search relevance: 63.79 | Views last month: 0 -
A method for judging feature of malignant tumor is described herein. The method comprises obtaining step, first comparing step, second comparing step, and judging step. The obtaining step...
Search relevance: 60.59 | Views last month: 0 -
Age plays a major role in tumor incidence and is an important consideration when modeling the carcinogenesis process or estimating cancer risks. Epidemiological data show that from adolescence...
Search relevance: 56.64 | Views last month: 0 -
Proton irradiation is touted for its improved tumor targeting due to the physical advantages of ion beams for radiotherapy. Recent studies from our laboratory have shown that in addition to...
Search relevance: 55.86 | Views last month: 0 -
Accumulating data support the concept that ionizing radiation therapy (RT) has the potential to convert the tumor into an in situ individualized vaccine; however this potential is rarely realized...
Search relevance: 55.52 | Views last month: 0 -
Proton irradiation is touted for its improved tumor targeting due to the physical advantages of ion beams for radiotherapy. Recent studies from our laboratory have shown that in addition to...
Search relevance: 55.30 | Views last month: 0 -
Accumulating data support the concept that ionizing radiation therapy (RT) has the potential to convert the tumor into an in situ individualized vaccine; however this potential is rarely realized...
Search relevance: 54.40 | Views last month: 0 -
Background A systems approach to understanding the etiology of schizophrenia requires a theory which is able to integrate genetic as well as neurodevelopmental factors. ...
Search relevance: 50.11 | Views last month: 0 -
Abstract Here we have reviewed the conventional definitions and fundamental characteristics of the two basic types of stem cells, embryonic stem cells (ESCs) and somatic stem cells...
Search relevance: 49.30 | Views last month: 0 -
Background Mutations in the CHK2 gene at chromosome 22q12.1 have been reported in families with Li-Fraumeni syndrome. Chk2 is an effector kinase that is activated in response to DNA...
Search relevance: 48.96 | Views last month: 1 -
This is a genome-wide approach to identifying genes persistently induced in the mouse mammary gland by acute whole body low dose ionizing radiation (10cGy) 1 and 4 weeks after exposure. Gene...
Search relevance: 46.96 | Views last month: 0 -
This is a genome-wide approach to identifying genes persistently induced in the mouse mammary gland by acute whole body low dose ionizing radiation (10cGy) 1 and 4 weeks after exposure. Gene...
Search relevance: 46.96 | Views last month: 0 -
In this study, fruit flies and their parasitic wasps were sent to the ISS to examine changes in host immunity and parasite virulence. Key findings from this work are as follows: (a) Spaceflight...
Search relevance: 45.82 | Views last month: 0 -
In this study, fruit flies and their parasitic wasps were sent to the ISS to examine changes in host immunity and parasite virulence. Key findings from this work are as follows: (a) Spaceflight...
Search relevance: 44.90 | Views last month: 0 -
In this study, fruit flies and their parasitic wasps were sent to the ISS to examine changes in host immunity and parasite virulence. Key findings from this work are as follows: (a) Spaceflight...
Search relevance: 44.90 | Views last month: 0
