Found 6 datasets matching "two-locus-model".
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Background In order to maintain populations as units of reproduction and thus enable anagenetic evolution, genetic factors must exist which prevent continuing reproductive separation or...
Search relevance: 274.36 | Views last month: 0 -
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the production of autoantibodies to a wide range of self-antigens. Recent genome screens have implicated...
Search relevance: 56.92 | Views last month: 0 -
Background Earlier methods for detecting major genes responsible for a quantitative trait rely critically upon a well-structured pedigree in which the segregation pattern of genes...
Search relevance: 54.33 | Views last month: 0 -
Background An A54T polymorphism at the fatty acid binding protein 2 (FABP2) locus was found to be associated with insulin resistance in non-diabetic Pima Indians. To see whether this...
Search relevance: 51.07 | Views last month: 0 -
Background Annotations of completely sequenced genomes reveal that nearly half of the genes identified are of unknown function, and that some belong to uncharacterized gene families. To...
Search relevance: 39.50 | Views last month: 0 -
Background Although vitamin D receptor (VDR) polymorphisms have been shown to be associated with abnormal glucose metabolism, the reported polymorphisms are unlikely to have any...
Search relevance: 30.17 | Views last month: 0
