Found 31 datasets matching "viral RNA".
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Background Recent studies of viral entry proteins from influenza, measles, human immunodeficiency virus, type 1 (HIV-1), and Ebola virus have shown, first with molecular modeling, and...
Search relevance: 188.49 | Views last month: 0 -
Background Post-transcriptional gene silencing (PTGS) by short interfering RNA has opened up new directions in the phenotypic mutation of cellular genes. However, its efficacy on...
Search relevance: 127.74 | Views last month: 0 -
Decay rates of infectious SARS-CoV-2 and viral RNA. This dataset is associated with the following publication: Korajkic, A., B. McMinn, A. Pemberton, J. Kelleher, and W. Ahmed. The comparison of...
Search relevance: 126.81 | Views last month: 0 -
Intraspecific variation in host infectiousness affects disease transmission dynamics in human, domestic animal, and many wildlife host-pathogen systems including avian influenza virus (AIV);...
Search relevance: 105.59 | Views last month: 0 -
Human immunodeficiency virus type 1 (HIV-1) and human T cell leukemia virus type II (HTLV-2) use a similar mechanism for –1 translational frameshifting to overcome the termination codon in ...
Search relevance: 69.71 | Views last month: 0 -
Background The hepadnaviral reverse transcriptase can synthesize DNA on its native RNA template within viral cores but it is usually unable to synthesize DNA employing exogenous nucleic...
Search relevance: 66.57 | Views last month: 0 -
We are developing retroviral-mediated gene transfer to human fibroblast-like synovial cells (FLS) as one approach to characterizing genetic pathways involved in synoviocyte pathophysiology. Prior...
Search relevance: 65.19 | Views last month: 0 -
EPA Method 1615 measures enteroviruses and noroviruses present in environmental and drinking waters. The viral ribonucleic acid (RNA) from water sample concentrates is extracted and tested for...
Search relevance: 63.19 | Views last month: 0 -
Intraspecific variation in pathogen shedding impacts disease transmission dynamics; therefore, understanding the host factors associated with individual variation in pathogen shedding is key to...
Search relevance: 60.51 | Views last month: 0 -
Hepatitis C virus (HCV) is an important human pathogen that affects ∼100 million people worldwide. Its RNA genome codes for a polyprotein, which is cleaved by viral and cellular proteases to...
Search relevance: 59.19 | Views last month: 0 -
The key enzyme in coronavirus polyprotein processing is the viral main proteinase, Mpro, a protein with extremely low sequence similarity to other viral and cellular proteinases. Here, the crystal...
Search relevance: 55.01 | Views last month: 0 -
Background Human herpesvirus-8 (HHV-8) is linked to the pathogenesis of Kaposi's sarcoma (KS), and the HHV-8 DNA load in peripheral blood mononuclear cells (PBMC) is associated with the...
Search relevance: 50.38 | Views last month: 0 -
Environmental variation has important effects on host-pathogen interactions, affecting large-scale ecological processes such as the severity and frequency of epidemics. However, less is known...
Search relevance: 49.26 | Views last month: 1 -
Theory of the evolution of pathogen specialization suggests that a specialist pathogen gains high fitness in one host, but this comes with fitness loss in other hosts. By contrast, a generalist...
Search relevance: 48.49 | Views last month: 0 -
This dataset contains results of genetic screening for Poecivirus from samples of black-capped chickadees (BCCH; Poecile atricapillus) with and without clinical signs of avian keratin disorder...
Search relevance: 47.58 | Views last month: 0 -
Background Many RNA viruses do not have a single, representative genome but instead form a set of related variants that has been called a quasispecies. The sequence variability of such...
Search relevance: 43.88 | Views last month: 0 -
Deformed wing virus (DWV) is a major pathogen of concern to apiculture, and recent reports have indicated the local predominance and potential virulence of recombinants between DWV and a related...
Search relevance: 42.98 | Views last month: 2 -
Piscine orthoreovirus genotype one (PRV-1) is the causative agent of heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar L.). The virus has also been found in...
Search relevance: 42.78 | Views last month: 0 -
This work is part of a study of the immunological effects of exposure to alternative flame retardants in avian species. For the pathology portion of the study, hatchling American kestrels (Falco...
Search relevance: 41.38 | Views last month: 0 -
Case counts of people newly reported with Chronic Hepatitis B and C. This surveillance data includes all confirmed and probable cases. NYC Heath Code §11.03(a) and §13.03(b) require that clinical...
Search relevance: 40.95 | Views last month: 6
