Found 20 datasets matching "viral-protein".
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Background Vaccinia virus gene B1R encodes a serine/threonine protein kinase. In vitro this protein kinase phosphorylates ribosomal proteins Sa and S2 and vaccinia virus protein H5R,...
Search relevance: 138.37 | Views last month: 0 -
Hepatitis C virus (HCV) is an important human pathogen that affects ∼100 million people worldwide. Its RNA genome codes for a polyprotein, which is cleaved by viral and cellular proteases to...
Search relevance: 124.21 | Views last month: 0 -
Hepatitis E virus (HEV) is the causative agent of hepatitis E, an acute form of viral hepatitis. The open reading frame 2 (ORF2) of HEV encodes the viral capsid protein, which can self-oligomerize...
Search relevance: 122.26 | Views last month: 0 -
The key enzyme in coronavirus polyprotein processing is the viral main proteinase, Mpro, a protein with extremely low sequence similarity to other viral and cellular proteinases. Here, the crystal...
Search relevance: 102.23 | Views last month: 0 -
Viral proteins derived from an enterically transmitted non-A/non-B viral hepatitis agent (HEV) are disclosed. In one embodiment, the protein is immunologically reactive with antibodies present in...
Search relevance: 78.40 | Views last month: 0 -
We are developing retroviral-mediated gene transfer to human fibroblast-like synovial cells (FLS) as one approach to characterizing genetic pathways involved in synoviocyte pathophysiology. Prior...
Search relevance: 63.85 | Views last month: 0 -
NCBI Virus is an integrative, value-added resource designed to support retrieval, display and analysis of a curated collection of virus sequences and large sequence datasets. Its goal is to...
Search relevance: 57.51 | Views last month: 31 -
Background Viral DNA-binding proteins have served as good models to study the biochemistry of transcription regulation and chromatin dynamics. Computational analysis of viral DNA-binding...
Search relevance: 54.60 | Views last month: 0 -
Background Current evidence suggests that lepidopteran baculoviruses may be divided into two phylogenetic groups based on their envelope fusion proteins. One group utilizes gp64, a low...
Search relevance: 54.43 | Views last month: 0 -
Background The mos proto-oncogene encodes a cytoplasmic serine/threonine-specific protein kinase with crucial function during meiotic cell division in vertebrates. Based on oncogenic...
Search relevance: 54.39 | Views last month: 0 -
Somatic coliphages are alternative indicators of fecal pollution and are attractive surrogate for viral pathogens. Here we report the draft genome sequences of three replicate plaques from a novel...
Search relevance: 53.18 | Views last month: 0 -
Background Studies examining herpesvirus-herpesvirus (cytomegalovirus (CMV)-Epstein-Barr virus (EBV)) interactions are limited, and many of the studies have been clinical observations...
Search relevance: 52.83 | Views last month: 0 -
Background Freshwater planarians are widely used as models for investigation of pattern formation and studies on genetic variation in populations. Despite extensive information on the...
Search relevance: 52.33 | Views last month: 1 -
Background Recent studies of viral entry proteins from influenza, measles, human immunodeficiency virus, type 1 (HIV-1), and Ebola virus have shown, first with molecular modeling, and...
Search relevance: 51.66 | Views last month: 0 -
VIDA is a new virus database that organizes open reading frames (ORFs) from partial and complete genomic sequences from animal viruses. Currently VIDA includes all sequences from GenBank for...
Search relevance: 48.07 | Views last month: 0 -
The global outbreak of clade 2.3.4.4b H5N1 highly pathogenic avian influenza (HPAI) virus has caused tremendous losses in poultry. Although turkeys are a smaller sector in poultry production...
Search relevance: 45.09 | Views last month: 1 -
Background The DNA single-strand annealing proteins (SSAPs), such as RecT, Redβ, ERF and Rad52, function in RecA-dependent and RecA-independent DNA recombination pathways. Recently, they...
Search relevance: 42.21 | Views last month: 0 -
Influenza A virus is a major respiratory pathogen in swine that leads to significant economic loss in the swine industry, and there is a critical need to improve on commercial vaccines....
Search relevance: 37.38 | Views last month: 0 -
Background The hepatic stellate cell is the primary cell type responsible for the excessive formation and deposition of connective tissue elements during the development of hepatic...
Search relevance: 32.86 | Views last month: 2 -
Two commercially available vaccines based on the recombinant herpes virus of turkeys (rHVT) vector were tested against a recent North American clade 2.3.4.4b HPAI virus isolate:...
Search relevance: 14.64 | Views last month: 2
