An examination of the effect of aerosolized Permanone insecticide on zebra finch susceptibility to West Nile virus: Data
Following building an aerosol exposure chamber in which we could expose domesticated zebra finches, we examined the effects of exposure to aerosolized Permanone® 30:30 insecticide (permethrin and piperonyl butoxide in soy oil vehicle) at ~103-106 x potential environmental concentrations on the response to experimental challenge with West Nile virus (WNV). Compared to vehicle control birds, WNV outcome was unchanged (65% of birds produced a viremia) in the ‘low’ exposure (9.52 mg/m3±3.13 SD permethrin) group, but reduced in the ‘high’ exposure (mean 376.5 mg/m3±27.9 SD permethrin) group (30% were viremic) (p < 0.05). After clearing WNV infection, birds treated with Permanone regained less body mass than vehicle treated birds (p < 0.001). Our study suggests that exposure to aerosolized Permanone insecticide at levels exceeding typical application rates has the potential to not change or mildly enhance a bird’s resistance to WNV.
Complete Metadata
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"fn": "Erik Hofmeister",
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|
| description | Following building an aerosol exposure chamber in which we could expose domesticated zebra finches, we examined the effects of exposure to aerosolized Permanone® 30:30 insecticide (permethrin and piperonyl butoxide in soy oil vehicle) at ~103-106 x potential environmental concentrations on the response to experimental challenge with West Nile virus (WNV). Compared to vehicle control birds, WNV outcome was unchanged (65% of birds produced a viremia) in the ‘low’ exposure (9.52 mg/m3±3.13 SD permethrin) group, but reduced in the ‘high’ exposure (mean 376.5 mg/m3±27.9 SD permethrin) group (30% were viremic) (p < 0.05). After clearing WNV infection, birds treated with Permanone regained less body mass than vehicle treated birds (p < 0.001). Our study suggests that exposure to aerosolized Permanone insecticide at levels exceeding typical application rates has the potential to not change or mildly enhance a bird’s resistance to WNV. |
| distribution |
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| identifier | http://datainventory.doi.gov/id/dataset/USGS_5a09b689e4b09af898c94770 |
| keyword |
[
"Insecticide",
"Laboratory animal model",
"Permanone",
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"disease",
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|
| modified | 2020-10-16T00:00:00Z |
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{
"name": "U.S. Geological Survey",
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| theme |
[
"Geospatial"
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|
| title | An examination of the effect of aerosolized Permanone insecticide on zebra finch susceptibility to West Nile virus: Data |
