Associations among NMR-measured inflammatory and metabolic biomarkers and accelerated aging in cardiac catheterization patients

This dataset was utilized to evaluate associations between accelerated epigenetic and transcriptomic age and NMR-measured metabolic and inflammatory biomarkers. It contains information on biological and chronological age, confounders, and NMR-measured 'omic profiles. This dataset is not publicly accessible because: The data is derived from medical records which cannot be disclosed per federal law (HIPPA) and existing data use agreements. It can be accessed through the following means: The data can be accessed via sending a request to the CATHGEN Executive Committee (https://dmpi.duke.edu/studies/cathgen). An approved IRB application may be required by the committee. Format: The data is tabular data containing columns specifying the epigenetic and transcriptomic age of the individuals along with NMR-measured metabolic biomarkers. Social and demographic confounders are are included within the dataset. This dataset is associated with the following publication: Raab, H., E. Hauser, L. Kwee, S. Shah, W. Kraus, and C. Ward-Caviness. Associations among NMR-measured inflammatory and metabolic biomarkers and accelerated aging in cardiac catheterization patients. Aging. Impact Journals, LLC, Orchard Park, NY, USA, 16(8): 6652-6672, (2024).

                                            [
  "020:00"
]
                                        

                                            {
  "fn": "Cavin Ward-Caviness",
  "hasEmail": "mailto:ward-caviness.cavin@epa.gov"
}
                                        

                                            []
                                        

                                            [
  "Aging",
  "NMR",
  "inflammation",
  "metabolic dysfunction",
  "transcriptomic aging"
]
                                        

                                            [
  "020:000"
]
                                        

                                            {
  "name": "U.S. EPA Office of Research and Development (ORD)",
  "subOrganizationOf": {
    "name": "U.S. Environmental Protection Agency",
    "subOrganizationOf": {
      "name": "U.S. Government"
    }
  }
}
                                        

                                            [
  "https://doi.org/10.18632/aging.205758",
  "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11087135"
]
                                        

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