Characterization data for trout liver S9 fractions used by Droge et al to measure the in vitro intrinsic clearance of cationic surfactants
This ScienceHub dataset provides characterization data for a pooled sample of trout liver S9 fractions that was used to study the in vitro intrinsic clearance of selected cationic surfactants. These data describe the activity of the pooled sample toward prototypical substrates for cytochrome P450 (CYP) 1A, glutathione-S-transferase, and UDP-glucuronosyltranserase. Also provided are the protein content and total CYP content of the sample and well as information pertaining to the size and gender of fish from which the original sample was obtained.
This dataset is associated with the following publication:
Droge, S., J. Armitage, J. Arnot, P. Fitzsimmons, and J. Nichols. Biotransformation Potential of Cationic Surfactants in Fish Assessed with Rainbow Trout Liver S9 Fractions. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, USA, 40(11): 3123-3136, (2021).
Complete Metadata
| accessLevel | public |
|---|---|
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "Patrick Fitzsimmons",
"hasEmail": "mailto:fitzsimmons.patrick@epa.gov"
}
|
| description | This ScienceHub dataset provides characterization data for a pooled sample of trout liver S9 fractions that was used to study the in vitro intrinsic clearance of selected cationic surfactants. These data describe the activity of the pooled sample toward prototypical substrates for cytochrome P450 (CYP) 1A, glutathione-S-transferase, and UDP-glucuronosyltranserase. Also provided are the protein content and total CYP content of the sample and well as information pertaining to the size and gender of fish from which the original sample was obtained. This dataset is associated with the following publication: Droge, S., J. Armitage, J. Arnot, P. Fitzsimmons, and J. Nichols. Biotransformation Potential of Cationic Surfactants in Fish Assessed with Rainbow Trout Liver S9 Fractions. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY. Society of Environmental Toxicology and Chemistry, Pensacola, FL, USA, 40(11): 3123-3136, (2021). |
| distribution |
[
{
"title": "Droge et al_cationic surfactants_ScienceHub_entry.xlsx",
"mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1521160/Droge%20et%20al_cationic%20surfactants_ScienceHub_entry.xlsx"
}
]
|
| identifier | https://doi.org/10.23719/1521160 |
| keyword |
[
"bioaccumulation assessment",
"biotransformation",
"cationic surfactant",
"liver S9 fraction",
"rainbow trout"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2021-03-25 |
| programCode |
[
"020:095"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
[
"https://doi.org/10.1002/etc.5189",
"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187044"
]
|
| rights |
null
|
| title | Characterization data for trout liver S9 fractions used by Droge et al to measure the in vitro intrinsic clearance of cationic surfactants |
