Skip to main content
U.S. flag

An official website of the United States government

This site is currently in beta, and your feedback is helping shape its ongoing development.

Data File for iAs Dose-response Manuscripts - Data files used in preparing four manuscripts describing dose-response methods that have been developed for the purposes of the EPA inorganic arsenic IRIS health assessment.

Published by U.S. EPA Office of Research and Development (ORD) | U.S. Environmental Protection Agency | Metadata Last Checked: August 02, 2025 | Last Modified: 2018-07-26
These datasets contain information used in support of tables, figures and conclusions made in four manuscripts related to EPA methods developed for the dose-response analysis of epidemiological studies of arsenic health effects. This dataset is associated with the following publications: Hobbie, K., K. Shao, C. Henning, W. Mendez, Jr, J. Lee, I. Cote, I. Druwe, A. Davis, and J. Gift. Use of study-specific MOE-like estimates to prioritize health effects from chemical exposure for analysis in human health assessments. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, NETHERLANDS, 144: 1-14, (2020). Mendez, W., K. Shao, J. Lee, I. Cote, I. Druwe, A. Davis, and J. Gift. Model Averaging Methods for the Evaluation of Dose-Response Model Uncertainty When Assessing the Suitability of Studies for Estimating Risk. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, NETHERLANDS, 143: 1-11, (2020). Allen, B., K. Shao, K. Hobie, W. Mendez Jr, J. Lee, I. Cote, I. Druwe, J. Gift, and A. Davis. Systematic dose-response of environmental epidemiologic studies: Dose and Response Pre-Analysis. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, NETHERLANDS, 142: 105810, (2020). Allen, B., K. Shao, K. Hobbie, W. Mendez Jr, J. Lee, I. Cote, I. Druwe, J. Gift, and A. Davis. Bayesian Hierarchical Dose-response Meta-analysis of Epidemiological Studies : Modeling and Target Population Prediction Methods. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, NETHERLANDS, 145: 106111, (2020).

Find Related Datasets

Click any tag below to search for similar datasets

Complete Metadata
accessLevel public
bureauCode 
                                            [
  "020:00"
]
contactPoint 
                                            {
  "fn": "Jeffrey Gift",
  "hasEmail": "mailto:gift.jeff@epa.gov"
}
description These datasets contain information used in support of tables, figures and conclusions made in four manuscripts related to EPA methods developed for the dose-response analysis of epidemiological studies of arsenic health effects. This dataset is associated with the following publications: Hobbie, K., K. Shao, C. Henning, W. Mendez, Jr, J. Lee, I. Cote, I. Druwe, A. Davis, and J. Gift. Use of study-specific MOE-like estimates to prioritize health effects from chemical exposure for analysis in human health assessments. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, NETHERLANDS, 144: 1-14, (2020). Mendez, W., K. Shao, J. Lee, I. Cote, I. Druwe, A. Davis, and J. Gift. Model Averaging Methods for the Evaluation of Dose-Response Model Uncertainty When Assessing the Suitability of Studies for Estimating Risk. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, NETHERLANDS, 143: 1-11, (2020). Allen, B., K. Shao, K. Hobie, W. Mendez Jr, J. Lee, I. Cote, I. Druwe, J. Gift, and A. Davis. Systematic dose-response of environmental epidemiologic studies: Dose and Response Pre-Analysis. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, NETHERLANDS, 142: 105810, (2020). Allen, B., K. Shao, K. Hobbie, W. Mendez Jr, J. Lee, I. Cote, I. Druwe, J. Gift, and A. Davis. Bayesian Hierarchical Dose-response Meta-analysis of Epidemiological Studies : Modeling and Target Population Prediction Methods. ENVIRONMENT INTERNATIONAL. Elsevier B.V., Amsterdam, NETHERLANDS, 145: 106111, (2020).
distribution 
                                            [
  {
    "title": "A_Summary_For_CaseControl_20161002_508.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/A_Summary_For_CaseControl_20161002_508.xlsx"
  },
  {
    "title": "A_Summary_For_Cohort_20180713_508.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/A_Summary_For_Cohort_20180713_508.xlsx"
  },
  {
    "title": "Bladder and Lung Cancer Dose response Read Me_508.docx",
    "mediaType": "application/vnd.openxmlformats-officedocument.wordprocessingml.document",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/Bladder%20and%20Lung%20Cancer%20Dose%20response%20Read%20Me_508.docx"
  },
  {
    "title": "Data_Dictionary-MOE_paper_508.docx",
    "mediaType": "application/vnd.openxmlformats-officedocument.wordprocessingml.document",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/Data_Dictionary-MOE_paper_508.docx"
  },
  {
    "title": "Data_Dictionary_MR1_paper_508.docx",
    "mediaType": "application/vnd.openxmlformats-officedocument.wordprocessingml.document",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/Data_Dictionary_MR1_paper_508.docx"
  },
  {
    "title": "Data_Dictionary_MR2_paper_508.docx",
    "mediaType": "application/vnd.openxmlformats-officedocument.wordprocessingml.document",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/Data_Dictionary_MR2_paper_508.docx"
  },
  {
    "title": "S1-Bates1995_CE5_508.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/S1-Bates1995_CE5_508.xlsx"
  },
  {
    "title": "S10-BC_Morbidity_Lifetable_10ugL_MLE_inh_bkg_0.31_508.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/S10-BC_Morbidity_Lifetable_10ugL_MLE_inh_bkg_0.31_508.xlsx"
  },
  {
    "title": "S11-BC_Morbidity_Lifetable_10ugL_MLE_inh_bkg_0.6_508.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/S11-BC_Morbidity_Lifetable_10ugL_MLE_inh_bkg_0.6_508.xlsx"
  },
  {
    "title": "S12-alternative_gamma_prior_results_508.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/S12-alternative_gamma_prior_results_508.xlsx"
  },
  {
    "title": "S2-Bates2004_DW4_508.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/S2-Bates2004_DW4_508.xlsx"
  },
  {
    "title": "S3-Chen_2010_NE_Taiwan_508.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/S3-Chen_2010_NE_Taiwan_508.xlsx"
  },
  {
    "title": "S4-Meliker2010_CE5_508.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/S4-Meliker2010_CE5_508.xlsx"
  },
  {
    "title": "S5-Gamma distribution for B_mean prior_508.docx",
    "mediaType": "application/vnd.openxmlformats-officedocument.wordprocessingml.document",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/S5-Gamma%20distribution%20for%20B_mean%20prior_508.docx"
  },
  {
    "title": "S5-Sawada_females_508.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/S5-Sawada_females_508.xlsx"
  },
  {
    "title": "S6 - bladder cancer lifetable results_508.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/S6%20-%20bladder%20cancer%20lifetable%20results_508.xlsx"
  },
  {
    "title": "S6-Sawada_males_508.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/S6-Sawada_males_508.xlsx"
  },
  {
    "title": "S7-Steinmaus2003_CE5_508.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/S7-Steinmaus2003_CE5_508.xlsx"
  },
  {
    "title": "S8-Steinmaus2013_CE5_508.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/S8-Steinmaus2013_CE5_508.xlsx"
  },
  {
    "title": "S8-final bladder cancer Stan runs_508.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/S8-final%20bladder%20cancer%20Stan%20runs_508.xlsx"
  },
  {
    "title": "S9-Wu2013_U&I_508.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/S9-Wu2013_U%26I_508.xlsx"
  },
  {
    "title": "bootstrap_bladder_case_num_adj_508.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/bootstrap_bladder_case_num_adj_508.xlsx"
  },
  {
    "title": "bootstrap_lung_cases_508.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/bootstrap_lung_cases_508.xlsx"
  },
  {
    "title": "bootstrap_mean_expo_march2016big_508.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1502484/bootstrap_mean_expo_march2016big_508.xlsx"
  }
]
identifier https://doi.org/10.23719/1502484
keyword 
                                            [
  "dose-response",
  "inorganic arsenic"
]
license https://pasteur.epa.gov/license/sciencehub-license.html
modified 2018-07-26
programCode 
                                            [
  "020:062"
]
publisher 
                                            {
  "name": "U.S. EPA Office of Research and Development (ORD)",
  "subOrganizationOf": {
    "name": "U.S. Environmental Protection Agency",
    "subOrganizationOf": {
      "name": "U.S. Government"
    }
  }
}
references 
                                            [
  "https://doi.org/10.1016/j.envint.2020.105810",
  "https://doi.org/10.1016/j.envint.2020.105857",
  "https://doi.org/10.1016/j.envint.2020.105986",
  "https://doi.org/10.1016/j.envint.2020.106111"
]
rights 
                                            null
title Data File for iAs Dose-response Manuscripts - Data files used in preparing four manuscripts describing dose-response methods that have been developed for the purposes of the EPA inorganic arsenic IRIS health assessment.

data.gov

An official website of the GSA's Technology Transformation Services

Looking for U.S. government information and services?
Visit USA.gov