Data from: Fructooligosaccharides (FOS) differentially modifies the in vitro gut microbiota in an age-dependent manner
A 24-h in vitro culturing method was used to determine whether fructooligosaccharide (FOS) treatment effects on the human gut microbiome has a differential effect by age, using fecal samples from 18 adults in 3 age groups with 6 individuals for each group, young adult (25–35 years of age), adult (36–50 years of age), and older adult (51–70 years of age). Data collected include: amplicon sequencing of the V1-V2 regions of the 16S rRNA gene (available in the NCBI Sequence Read Archive associated with BioProject PRJNA883714: https://www.ncbi.nlm.nih.gov/bioproject/PRJNA883714), total bacterial qPCR, Bifidobacterium genus specific q-PCR, and short chain fatty acid concentrations.
Resources in this dataset:
Resource Title: Sample metadata
File Name: FOS_sample_attributes.csv
Resource Title: Short Chain Fatty Acid concentrations
File Name: FOS_SCFA_data.csv
Resource Title: Total bacterial and Bifidobacterium genus qPCR
File Name: total_bacteria_and_Bifidobacterium_specific_qPCR.csv
Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[
"005:18"
]
|
| contactPoint |
{
"fn": "Narrowe, Adrienne",
"hasEmail": "mailto:adrienne.narrowe@usda.gov"
}
|
| description | <p>A 24-h in vitro culturing method was used to determine whether fructooligosaccharide (FOS) treatment effects on the human gut microbiome has a differential effect by age, using fecal samples from 18 adults in 3 age groups with 6 individuals for each group, young adult (25–35 years of age), adult (36–50 years of age), and older adult (51–70 years of age). Data collected include: amplicon sequencing of the V1-V2 regions of the 16S rRNA gene (available in the NCBI Sequence Read Archive associated with BioProject PRJNA883714: <a href="https://www.ncbi.nlm.nih.gov/bioproject/PRJNA883714">https://www.ncbi.nlm.nih.gov/bioproject/PRJNA883714</a>), total bacterial qPCR, Bifidobacterium genus specific q-PCR, and short chain fatty acid concentrations. </p> <p>Resources in this dataset:</p> <ul> <li> <p>Resource Title: Sample metadata File Name: FOS_sample_attributes.csv</p> </li> <li> <p>Resource Title: Short Chain Fatty Acid concentrations File Name: FOS_SCFA_data.csv</p> </li> <li> <p>Resource Title: Total bacterial and Bifidobacterium genus qPCR File Name: total_bacteria_and_Bifidobacterium_specific_qPCR.csv</p> </li> </ul> |
| distribution |
[
{
"@type": "dcat:Distribution",
"title": "FOS_sample_attributes_0.csv",
"format": "csv",
"mediaType": "application/csv",
"downloadURL": "https://ndownloader.figshare.com/files/44540789"
},
{
"@type": "dcat:Distribution",
"title": "FOS_SCFA_data_0.csv",
"format": "csv",
"mediaType": "text/plain",
"downloadURL": "https://ndownloader.figshare.com/files/44540792"
},
{
"@type": "dcat:Distribution",
"title": "total_bacteria_and_Bifidobacterium_specific_qPCR_0.csv",
"format": "csv",
"mediaType": "application/csv",
"downloadURL": "https://ndownloader.figshare.com/files/44540795"
}
]
|
| identifier | 10.15482/USDA.ADC/1529151 |
| keyword |
[
"16S rRNA sequence data",
"ARS",
"NP306",
"bifidobacteria",
"data.gov",
"fructooligosaccharides",
"prebiotics",
"short chain fatty acids"
]
|
| license | https://creativecommons.org/licenses/by/4.0/ |
| modified | 2025-11-21 |
| programCode |
[
"005:040"
]
|
| publisher |
{
"name": "Agricultural Research Service",
"@type": "org:Organization"
}
|
| spatial |
"{"type": "Point", "coordinates": [-75.187092456102, 40.078126249741]}"
|
| temporal | 2021-05-01/2021-05-01 |
| title | Data from: Fructooligosaccharides (FOS) differentially modifies the in vitro gut microbiota in an age-dependent manner |
