Data from: Swine influenza A replicon particle and live attenuated influenza virus vaccines induce differential systemic and mucosal antibody and T cell responses
The dataset contains measurements from a swine research study evaluating influenza A immune responses and protection for replicon particle and live attenuated influenza virus vaccines. The research study was conducted by United States Department of Agriculture, Agricultural Research Service (USDA-ARS) scientists and postdoctoral scientists at the National Animal Disease Center, USDA-ARS to characterize heterologous virus immunity from live attenuated influenza A virus vaccines and IAV replicon particle vaccines. A better understanding of vaccine immune responses to heterologous viruses will aid in development of improved swine IAV vaccination strategies. The dataset contains lesion scores, virus shedding in nasal swabs and bronchoalveolar lavage fluid, serum and bronchoalveolar lavage fluid antibody responses, and isolated blood and lung T cell responses.
Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[
"005:18"
]
|
| contactPoint |
{
"fn": "Wymore Brand, Meghan",
"hasEmail": "mailto:meghan.brand@usda.gov"
}
|
| description | <p dir="ltr">The dataset contains measurements from a swine research study evaluating influenza A immune responses and protection for replicon particle and live attenuated influenza virus vaccines. The research study was conducted by United States Department of Agriculture, Agricultural Research Service (USDA-ARS) scientists and postdoctoral scientists at the National Animal Disease Center, USDA-ARS to characterize heterologous virus immunity from live attenuated influenza A virus vaccines and IAV replicon particle vaccines. A better understanding of vaccine immune responses to heterologous viruses will aid in development of improved swine IAV vaccination strategies. The dataset contains lesion scores, virus shedding in nasal swabs and bronchoalveolar lavage fluid, serum and bronchoalveolar lavage fluid antibody responses, and isolated blood and lung T cell responses.</p> |
| distribution |
[
{
"@type": "dcat:Distribution",
"title": "Ag Data Commons LAIV-RP Vaccine.xlsx",
"format": "xlsx",
"mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
"downloadURL": "https://ndownloader.figshare.com/files/56918372"
}
]
|
| identifier | 10.15482/USDA.ADC/29591348.v1 |
| keyword |
[
"Swine -- Diseases",
"influenza A virus",
"vaccine"
]
|
| license | https://www.usa.gov/publicdomain/label/1.0/ |
| modified | 2025-08-18 |
| programCode |
[
"005:040"
]
|
| publisher |
{
"name": "Agricultural Research Service",
"@type": "org:Organization"
}
|
| temporal | 2020-01-01/2024-12-01 |
| title | Data from: Swine influenza A replicon particle and live attenuated influenza virus vaccines induce differential systemic and mucosal antibody and T cell responses |
