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Dermal metafile for six studies for permeability estimation

Published by U.S. EPA Office of Research and Development (ORD) | U.S. Environmental Protection Agency | Metadata Last Checked: August 02, 2025 | Last Modified: 2021-03-17
Dermal absorption is an important route of exposure that includes pharmaceuticals, consumer products and occupational exposures. "httk" is being developed as a tool to predict internal dose after exposure. The dermal route will be added to this package in order to account for dermal exposure. This dataset is associated with the following publication: Evans, M., T. Moxon, G. Lian, B. Deacon, T. Chen, L. Adams, A. Meade, and J. Wambaugh. A regression analysis using simple descriptors for multiple dermal datasets: Going from individual membranes to the full skin. JOURNAL OF APPLIED TOXICOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, USA, 43(6): 940-950, (2023).

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