Endothelial [Ca2+]iis an integrating signal for the vascular tone in rat aortae
Although various endothelium-dependent relaxing factors (endothelial autacoids) are released upon the elevation of endothelial cytosolic free Ca2+concentration (EC [Ca2+]i), the quantitative relationship between EC [Ca2+]iand vascular tone remains to be established. Moreover, whether the basal release of endothelial autacoids is modulated by basal EC [Ca2+]iis still unclear. We assessed these issues by using a novel method that allows simultaneous recording of EC [Ca2+]iand vascular displacement in dissected rat aortic segments.
Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[
"009:25"
]
|
| contactPoint |
{
"fn": "NIH",
"@type": "vcard:Contact",
"hasEmail": "mailto:info@nih.gov"
}
|
| description | Although various endothelium-dependent relaxing factors (endothelial autacoids) are released upon the elevation of endothelial cytosolic free Ca2+concentration (EC [Ca2+]i), the quantitative relationship between EC [Ca2+]iand vascular tone remains to be established. Moreover, whether the basal release of endothelial autacoids is modulated by basal EC [Ca2+]iis still unclear. We assessed these issues by using a novel method that allows simultaneous recording of EC [Ca2+]iand vascular displacement in dissected rat aortic segments. |
| distribution |
[
{
"@type": "dcat:Distribution",
"title": "Official Government Data Source",
"mediaType": "text/html",
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"downloadURL": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC34108/"
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|
| identifier | https://healthdata.gov/api/views/4qdm-b9ic |
| issued | 2025-07-14 |
| keyword |
[
"aortic-segments",
"endothelial-calcium",
"nih",
"vascular-tone",
"vasorelaxation"
]
|
| landingPage | https://healthdata.gov/d/4qdm-b9ic |
| modified | 2025-09-29 |
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]
|
| publisher |
{
"name": "National Institutes of Health",
"@type": "org:Organization"
}
|
| theme |
[
"NIH"
]
|
| title | Endothelial [Ca2+]iis an integrating signal for the vascular tone in rat aortae |
