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Evaluation of Variability across Rat Acute Oral Systemic Toxicity Studies

Published by U.S. EPA Office of Research and Development (ORD) | U.S. Environmental Protection Agency | Metadata Last Checked: August 02, 2025 | Last Modified: 2022-03-15
Dataset for Karmaus et al. journal article 'Evaluation of Variability across Rat Acute Oral Systemic Toxicity Studies', published in Toxicological Sciences in July 2022 ( https://doi.org/10.1093/toxsci/kfac042). The Excel data file is from the following link in the article: The compiled data allowed for comprehensive characterization of the variability and performance for the rat acute oral toxicity study. The data set is available for download via the National Toxicology Program’s Integrated Chemical Environment (https://ice.ntp.niehs.nih.gov/). This dataset is associated with the following publication: Karmaus, A., K. Mansouri, K. To, B. Blake, J. Fitzpatrick, J. Strickland, G. Patlewicz, D. Allen, W. Casey, and N. Kleinstreuer. Evaluation of Variability Across Rat Acute Oral Systemic Toxicity Studies. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 188(1): 34-47, (2022).

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