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Hughes_A-0gb9_EH-TBB and BEH-TEBP in vitro dermal absorption 05/24/2017

Published by U.S. EPA Office of Research and Development (ORD) | U.S. Environmental Protection Agency | Metadata Last Checked: August 02, 2025 | Last Modified: 2018-10-22
The data is on 4 tabs, separated by species (rat, human) and chemical (EH-TBB and BEH_TEBP). The data is by cell (2-4/skin), and includes %dose in receptor fluid over time, % unabsorbed, % absorbed and % penetrated. This dataset is associated with the following publication: Knudsen, G., M. Hughes, J.M. Sanders, S. Hall, and L. Birnbaum. Estimation of human percutaneous bioavailability for two novel brominated flame retardants, 2-ethylhexyl tetrabromobenzoate (EH-TBB) and bis(2-ethylhexyl) tetrabromophthalate (BEH-TEBP), using the parallelogram approach. TOXICOLOGY AND APPLIED PHARMACOLOGY. Academic Press Incorporated, Orlando, FL, USA, 311: 117-127, (2016).

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