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Human BDCM Mulit-Route PBPK Model
This data set contains the code for the BDCM human multi-route model written in the programming language acsl. The final published manuscript is provided since it contains all the model parameters and data (from published literature).
This dataset is associated with the following publication:
Kenyon , E., T.L. Leavens, C. Eklund , and R. Pegram. Development and Application of a Human PBPK Model for Bromodichloromethane (BDCM) to Investigate Impacts of Multi-Route Exposure. JOURNAL OF APPLIED TOXICOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, USA, 36(9): 1095-1111, (2015).
Complete Metadata
| accessLevel | public |
|---|---|
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "Elaina Kenyon",
"hasEmail": "mailto:kenyon.elaina@epa.gov"
}
|
| describedBy | https://pasteur.epa.gov/uploads/10.23719/1407542/documents/DataDictionary_BDCMPBPK.pdf |
| describedByType | application/pdf |
| description | This data set contains the code for the BDCM human multi-route model written in the programming language acsl. The final published manuscript is provided since it contains all the model parameters and data (from published literature). This dataset is associated with the following publication: Kenyon , E., T.L. Leavens, C. Eklund , and R. Pegram. Development and Application of a Human PBPK Model for Bromodichloromethane (BDCM) to Investigate Impacts of Multi-Route Exposure. JOURNAL OF APPLIED TOXICOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, USA, 36(9): 1095-1111, (2015). |
| distribution |
[
{
"title": "BDCMPBPKMs.pdf",
"mediaType": "application/pdf",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1407542/BDCMPBPKMs.pdf"
},
{
"title": "BDCM_inhCSL.pdf",
"mediaType": "application/pdf",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1407542/BDCM_inhCSL.pdf"
},
{
"title": "GlobalSensitivityAnalysis_BDCMpbpk.pdf",
"mediaType": "application/pdf",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1407542/GlobalSensitivityAnalysis_BDCMpbpk.pdf"
},
{
"title": "LocalSensitivityAnalysis_BDCMpbpk.pdf",
"mediaType": "application/pdf",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1407542/LocalSensitivityAnalysis_BDCMpbpk.pdf"
},
{
"title": "VmaxKm_HanesWolfPlot_bdcm.pdf",
"mediaType": "application/pdf",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1407542/VmaxKm_HanesWolfPlot_bdcm.pdf"
}
]
|
| identifier | https://doi.org/10.23719/1407542 |
| keyword |
[
"acslx",
"bromodichloromethane",
"disinfection byproducts",
"model code",
"multi-route",
"pbpk",
"physiologically-based pharmacokinetic model"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2015-12-01 |
| programCode |
[
"020:096"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
[
"https://doi.org/10.1002/jat.3269"
]
|
| rights |
null
|
| title | Human BDCM Mulit-Route PBPK Model |
