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Hypothetical Aggregate Exposure Pathway Network

Published by U.S. EPA Office of Research and Development (ORD) | U.S. Environmental Protection Agency | Metadata Last Checked: August 02, 2025 | Last Modified: 2018-08-06
This data set contains R code for a hypothetical exposure model described in the manuscript "A quantitative source-to-outcome case study to demonstrate the integration of human health and ecological endpoints using the Aggregate Exposure Pathway and Adverse Outcome Pathway frameworks". Additionally, this data set contains an Excel file that provides the range of parameters used in Monte Carlo simulations to generate iterations of the exposure network. This dataset is associated with the following publication: Hines, D., R. Conolly, and A. Jarabek. A quantitative source-to-outcome case study to demonstrate the integration of human health and ecological endpoints using the Aggregate Exposure Pathway and Adverse Outcome Pathway frameworks. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 53(8): 11002-11012, (2019).

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