IMPACT OF E-CIGARETTE FLAVORING AGENTS ON ACTIVITY OF MICROSOMAL RECOMBINANT CYP2A6, THE PRIMARY NICOTINE-METABOLIZING-ENZYME
Most of the data illustrates the effects that some e-cigarette flavoring agents, as well as some of the chemical components of those flavoring agents, directly have on the cytochrome P450 2A6 enzyme activity.
This dataset is associated with the following publication:
Winters, B., T. Kochar, P. Clapp, I. Jaspers, and M. Madden. Impact of E-Cigarette Flavoring Agents on Activity of Microsomal Recombinant CYP2A6, The Primary Nicotine-Metabolizing-Enzyme. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, USA, 33(7): 1689-1697, (2020).
Complete Metadata
| accessLevel | public |
|---|---|
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "Michael Madden",
"hasEmail": "mailto:madden.michael@epa.gov"
}
|
| description | Most of the data illustrates the effects that some e-cigarette flavoring agents, as well as some of the chemical components of those flavoring agents, directly have on the cytochrome P450 2A6 enzyme activity. This dataset is associated with the following publication: Winters, B., T. Kochar, P. Clapp, I. Jaspers, and M. Madden. Impact of E-Cigarette Flavoring Agents on Activity of Microsomal Recombinant CYP2A6, The Primary Nicotine-Metabolizing-Enzyme. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, USA, 33(7): 1689-1697, (2020). |
| distribution |
[
{
"title": "data_summary fig 3 25nov2019.pdf",
"mediaType": "application/pdf",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1506082/data_summary%20fig%203%20%20%2025nov2019.pdf"
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"title": "data_summary fig 4 25nov2019.pdf",
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"mediaType": "application/pdf",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1506082/data_summary%20fig7%20%2025nov2019.pdf"
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|
| identifier | https://doi.org/10.23719/1506082 |
| keyword |
[
"cellular volatiles",
"cytochromeP450",
"high-throughput in vitro screening assay"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2019-12-10 |
| programCode |
[
"020:094"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
[
"https://doi.org/10.1021/acs.chemrestox.9b00514"
]
|
| rights |
null
|
| title | IMPACT OF E-CIGARETTE FLAVORING AGENTS ON ACTIVITY OF MICROSOMAL RECOMBINANT CYP2A6, THE PRIMARY NICOTINE-METABOLIZING-ENZYME |