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In silico site-directed mutagenesis informs species-specific predictions of chemical susceptibility derived from the Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS)
All data associated with publication are publicly available online at https://datadryad.org/ by searching doi:10.5061/dryad.2tg6967
Upon accessing data on datadryad.org:
Data descriptions are found with Supplemental Data presented in the pdf (Supplementary Data.pdf (600.4 Kb)).
Data description of supplemental Data (Supplementary Data File.xlsx (1.167 Mb)) is provided below:
Tabs one, two, and three contain the raw data for acetylcholinesterase (AChE) Level 1 (Figure 1A), Level 2 (Figure 1B), and Level 3 (Table 2) SeqAPASS analysis, respectively. Tab four contains the raw data for AChE Level 3 improved SeqAPASS analysis (Table 5). Tabs five, six, and seven contain the raw data for ecdysone receptor (EcR) Level 1 (Figure 2A), Level 2 (Figure 2B), and Level 3 (Table 6) SeqAPASS analysis, respectively. Tab eight contains the raw data for EcR Level 3 improved SeqAPASS analysis (Table 8).
This dataset is associated with the following publication:
Doering, J., S. Lee, K. Kristiansen, L. Evenseth, M. Barron, I. Sylte, and C. LaLone. In silico site-directed mutagenesis informs species-specific predictions of chemical susceptibility derived from the Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) tool.. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 166(1): 131-145, (2018).
Complete Metadata
| accessLevel | public |
|---|---|
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "Carlie Lalone",
"hasEmail": "mailto:lalone.carlie@epa.gov"
}
|
| description | All data associated with publication are publicly available online at https://datadryad.org/ by searching doi:10.5061/dryad.2tg6967 Upon accessing data on datadryad.org: Data descriptions are found with Supplemental Data presented in the pdf (Supplementary Data.pdf (600.4 Kb)). Data description of supplemental Data (Supplementary Data File.xlsx (1.167 Mb)) is provided below: Tabs one, two, and three contain the raw data for acetylcholinesterase (AChE) Level 1 (Figure 1A), Level 2 (Figure 1B), and Level 3 (Table 2) SeqAPASS analysis, respectively. Tab four contains the raw data for AChE Level 3 improved SeqAPASS analysis (Table 5). Tabs five, six, and seven contain the raw data for ecdysone receptor (EcR) Level 1 (Figure 2A), Level 2 (Figure 2B), and Level 3 (Table 6) SeqAPASS analysis, respectively. Tab eight contains the raw data for EcR Level 3 improved SeqAPASS analysis (Table 8). This dataset is associated with the following publication: Doering, J., S. Lee, K. Kristiansen, L. Evenseth, M. Barron, I. Sylte, and C. LaLone. In silico site-directed mutagenesis informs species-specific predictions of chemical susceptibility derived from the Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) tool.. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 166(1): 131-145, (2018). |
| distribution |
[
{
"title": "https://datadryad.org/",
"accessURL": "https://datadryad.org/"
}
]
|
| identifier | https://doi.org/10.23719/1432264 |
| keyword |
[
"adverse outcome pathway",
"cross-species extrapolation",
"ecotoxicology",
"honey bee",
"networks",
"screening and prioritization"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2018-07-30 |
| programCode |
[
"020:095"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
[
"https://doi.org/10.1093/toxsci/kfy186"
]
|
| rights |
null
|
| title | In silico site-directed mutagenesis informs species-specific predictions of chemical susceptibility derived from the Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) |
