KodavantiP-Acute_HSAB_AOP_Neurotox_Science Hub Data 090319
Neurotox data on in silico predicted chemicals to cause protein adducts in peripheral neurons. Includes cytotoxicity (LDH release), changes in neuron network architecture using high content imaging and neurophysiology via microelectrode arrays.
This dataset is associated with the following publication:
Johnstone, A., C. Mack, M. Valdez, T. Shafer, D. Herr, P. Kodavanti, and R. Lo Pachin. Acute In Vitro Effects on Embryonic Rat Dorsal Root Ganglion (DRG) Cultures by In Silico Predicted Neurotoxic Chemicals: Evaluations on Cytotoxicity, Neurite Length, and Neurophysiology.. TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, USA, 69(104989): 1, (2020).
Complete Metadata
| accessLevel | public |
|---|---|
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "Prasada Kodavanti",
"hasEmail": "mailto:kodavanti.prasada@epa.gov"
}
|
| description | Neurotox data on in silico predicted chemicals to cause protein adducts in peripheral neurons. Includes cytotoxicity (LDH release), changes in neuron network architecture using high content imaging and neurophysiology via microelectrode arrays. This dataset is associated with the following publication: Johnstone, A., C. Mack, M. Valdez, T. Shafer, D. Herr, P. Kodavanti, and R. Lo Pachin. Acute In Vitro Effects on Embryonic Rat Dorsal Root Ganglion (DRG) Cultures by In Silico Predicted Neurotoxic Chemicals: Evaluations on Cytotoxicity, Neurite Length, and Neurophysiology.. TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, USA, 69(104989): 1, (2020). |
| distribution |
[
{
"title": "KodavantiP_Acute_HSAB_AOP_Neurotox_Science Hub.xlsx",
"mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1504280/KodavantiP_Acute_HSAB_AOP_Neurotox_Science%20Hub.xlsx"
}
]
|
| identifier | https://doi.org/10.23719/1504280 |
| keyword |
[
"AOP",
"Dorsal Root Ganglion",
"Electrophilicity",
"Microelectrode array",
"Neurite length",
"Neuropathy",
"cytotoxicity"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2019-06-07 |
| programCode |
[
"020:095"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
[
"https://doi.org/10.1016/j.tiv.2020.104989"
]
|
| rights |
null
|
| title | KodavantiP-Acute_HSAB_AOP_Neurotox_Science Hub Data 090319 |
