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Liquid Application Dosing Alters Air-Liquid-Interface Bronchial Epithelial Culture Physiology and Toxicity Testing Relevant Endpoints

Published by U.S. EPA Office of Research and Development (ORD) | U.S. Environmental Protection Agency | Metadata Last Checked: August 02, 2025 | Last Modified: 2022-05-09
Data accompanying the manuscript titled, "Liquid Application Dosing Alters Air-Liquid-Interface Bronchial Epithelial Culture Physiology and Toxicity Testing Relevant Endpoints" Authors: Nicholas M. Mallek, Elizabeth M. Martin, Lisa A. Dailey, and Shaun D. McCullough. This dataset is associated with the following publication: Mallek, N., E. Martin, L. Dailey, and S. McCullough. Liquid Application Dosing Alters the Physiology of Air-Liquid Interface (ALI) Primary Human Bronchial Epithelial Cell/Lung Fibroblast Co-Cultures and In Vitro Testing Relevant Endpoints. Frontiers in Toxicology. Frontiers, Lausanne, SWITZERLAND, 5: 1264331, (2023).

Resources

11 resources available

  • Liquid Application Manuscript Prism File.zip

    APPLICATION/X-ZIP-COMPRESSED
    Download

  • Mallek et al_Liquid Application Data_PHBEC 24h Gene Lists_Raw_Thresholded.xlsx

    APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
    Download

  • Mallek et al_Liquid Application Data_PHBEC 6h Gene Lists_Raw_Thresholded.xlsx

    APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
    Download

  • Mallek et al_Liquid Application Data_TEER and FITC.xlsx

    APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
    Download

  • Mallek et al_Liquid Application_Data_Analysis of Re-Sub CBF_Processed Data.xlsx

    APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
    Download

  • Mallek et al_Liquid Application_Data_Analysis of Re-Sub Rep3-5 Export_RAW DATA.xls

    APPLICATION/VND.MS-EXCEL
    Download

  • Mallek et al_Liquid Application_Data_Growth Factor ELISA.xlsx

    APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
    Download

  • Mallek et al_Liquid Application_ERK Densitometry.xlsx

    APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
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  • Mallek et al_Liquid Application_HIF1a Densitometry.xlsx

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  • Mallek et al_Liquid Application_Western Blots.pdf

    APPLICATION/PDF
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  • Mallek et al_Liquid Application_p38 Densitometry.xlsx

    APPLICATION/VND.OPENXMLFORMATS-OFFICEDOCUMENT.SPREADSHEETML.SHEET
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Complete Metadata
accessLevel public
bureauCode 
                                            [
  "020:00"
]
contactPoint 
                                            {
  "fn": "Shaun McCullough",
  "hasEmail": "mailto:mccullough.shaun@epa.gov"
}
description Data accompanying the manuscript titled, "Liquid Application Dosing Alters Air-Liquid-Interface Bronchial Epithelial Culture Physiology and Toxicity Testing Relevant Endpoints" Authors: Nicholas M. Mallek, Elizabeth M. Martin, Lisa A. Dailey, and Shaun D. McCullough. This dataset is associated with the following publication: Mallek, N., E. Martin, L. Dailey, and S. McCullough. Liquid Application Dosing Alters the Physiology of Air-Liquid Interface (ALI) Primary Human Bronchial Epithelial Cell/Lung Fibroblast Co-Cultures and In Vitro Testing Relevant Endpoints. Frontiers in Toxicology. Frontiers, Lausanne, SWITZERLAND, 5: 1264331, (2023).
distribution 
                                            [
  {
    "title": "Liquid Application Manuscript Prism File.zip",
    "mediaType": "application/x-zip-compressed",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1526421/Liquid%20Application%20Manuscript%20Prism%20File.zip"
  },
  {
    "title": "Mallek et al_Liquid Application Data_PHBEC 24h Gene Lists_Raw_Thresholded.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1526421/Mallek%20et%20al_Liquid%20Application%20Data_PHBEC%2024h%20Gene%20Lists_Raw_Thresholded.xlsx"
  },
  {
    "title": "Mallek et al_Liquid Application Data_PHBEC 6h Gene Lists_Raw_Thresholded.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1526421/Mallek%20et%20al_Liquid%20Application%20Data_PHBEC%206h%20Gene%20Lists_Raw_Thresholded.xlsx"
  },
  {
    "title": "Mallek et al_Liquid Application Data_TEER and FITC.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1526421/Mallek%20et%20al_Liquid%20Application%20Data_TEER%20and%20FITC.xlsx"
  },
  {
    "title": "Mallek et al_Liquid Application_Data_Analysis of Re-Sub CBF_Processed Data.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1526421/Mallek%20et%20al_Liquid%20Application_Data_Analysis%20of%20Re-Sub%20CBF_Processed%20Data.xlsx"
  },
  {
    "title": "Mallek et al_Liquid Application_Data_Analysis of Re-Sub Rep3-5 Export_RAW DATA.xls",
    "mediaType": "application/vnd.ms-excel",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1526421/Mallek%20et%20al_Liquid%20Application_Data_Analysis%20of%20Re-Sub%20Rep3-5%20Export_RAW%20DATA.xls"
  },
  {
    "title": "Mallek et al_Liquid Application_Data_Growth Factor ELISA.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1526421/Mallek%20et%20al_Liquid%20Application_Data_Growth%20Factor%20ELISA.xlsx"
  },
  {
    "title": "Mallek et al_Liquid Application_ERK Densitometry.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1526421/Mallek%20et%20al_Liquid%20Application_ERK%20Densitometry.xlsx"
  },
  {
    "title": "Mallek et al_Liquid Application_HIF1a Densitometry.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1526421/Mallek%20et%20al_Liquid%20Application_HIF1a%20Densitometry.xlsx"
  },
  {
    "title": "Mallek et al_Liquid Application_Western Blots.pdf",
    "mediaType": "application/pdf",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1526421/Mallek%20et%20al_Liquid%20Application_Western%20Blots.pdf"
  },
  {
    "title": "Mallek et al_Liquid Application_p38 Densitometry.xlsx",
    "mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
    "downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1526421/Mallek%20et%20al_Liquid%20Application_p38%20Densitometry.xlsx"
  }
]
identifier https://doi.org/10.23719/1526421
keyword 
                                            [
  "ALI",
  "NAMs",
  "air-liquid inter",
  "bronchial",
  "chlorothalonil",
  "in vitro",
  "inhalation",
  "primary"
]
license https://pasteur.epa.gov/license/sciencehub-license.html
modified 2022-05-09
programCode 
                                            [
  "020:000"
]
publisher 
                                            {
  "name": "U.S. EPA Office of Research and Development (ORD)",
  "subOrganizationOf": {
    "name": "U.S. Environmental Protection Agency",
    "subOrganizationOf": {
      "name": "U.S. Government"
    }
  }
}
references 
                                            [
  "https://doi.org/10.3389/ftox.2023.1264331"
]
rights 
                                            null
title Liquid Application Dosing Alters Air-Liquid-Interface Bronchial Epithelial Culture Physiology and Toxicity Testing Relevant Endpoints

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