Mild Thyroid Hormone Insufficiency During Development Compromises Activity-Dependent Neuroplasticity in the Hippocampus of Adult Male Rats

Published by U.S. EPA Office of Research and Development (ORD) | U.S. Environmental Protection Agency | Metadata Last Checked: August 02, 2025 | Last Modified: 2015-10-27

behavioral measures of learning and memory in adult offspring of rats treated with thyroid hormone synthesis inhibitor, propylthiouracil. Electrophysiological measures of 'memory' in form of plasticity model known as long term potentiation (LTP) Molecular changes induced by LTP. This dataset is associated with the following publication: Gilbert , M., K. Sanchez-Huerta, and C. Wood. Mild Thyroid Hormone Insufficiency During Development Compromises Activity-Dependent Neuroplasticity in the Hippocampus of Adult Make Rats. ENDOCRINOLOGY. Endocrine Society, 157(2): 774-87, (2016).

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bureauCode	[ "020:00" ]
identifier	A-v42b-403
programCode	[ "020:000" ]
references	[ "https://doi.org/10.1210/en.2015-1643" ]
rights	null